Evening Primrose Oil

Reviewed on 9/10/2021

What Is Evening Primrose Oil and How Does It Work?

What Are the Dosages of Evening Primrose Oil?

Dosages of Evening Primrose Oil:

  • Eczema, Atopic
    • 4-6 g orally daily
  • Mastalgia
    • 3-4 g orally daily
  • Premenstrual Syndrome
    • 2-4 g orally daily
  • Rheumatoid Arthritis
    • 540 mg-2.8 g orally daily

Dosage Considerations – Should be Given as Follows:

  • See “Suggested Dosing”


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What Are Side Effects Associated with Using Evening Primrose Oil?

Common side effects of Evening Primrose Oil include:

  • Headache
  • Indigestion
  • Nausea
  • Pregnancy complications
  • Soft stools

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

What Other Drugs Interact with Evening Primrose Oil?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first.

  • Evening Primrose Oil has no known severe, serious, moderate, or mild interactions with other drugs.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.

What Are Warnings and Precautions for Evening Primrose Oil?


  • This medication contains evening primrose oil. Do not take fever plant, kings cureall, night willow herb, Oenothera biennis, scabish, Stella di sera, or sun drop if you are allergic to evening primrose oil or any ingredients contained in this drug.
  • Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.


  • None Reported

Effects of Drug Abuse

  • No information available

Short-Term Effects

  • See "What Are Side Effects Associated with Using Evening Primrose Oil?”

Long-Term Effects

  • See "What Are Side Effects Associated with Using Evening Primrose Oil?”


Pregnancy and Lactation

  • Do not use evening primrose oil in pregnancy. The risks involved outweigh the potential benefits. Safer alternatives exist.
  • Evening Primrose Oil is unsafe to use while breastfeeding.
Medscape. Evening Primrose Oil.

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