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Lactulose (cont.)

Medical and Pharmacy Editor:

What Are Warnings and Precautions for Lactulose?


  • This medication contains lactulose. Do not take Enulose, Kristalose, Constulose or Generlac, if you are allergic to lactulose or any ingredients contained in this drug.
  • Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.


Effects of Drug Abuse

  • No information available

Short-Term Effects

  • See "What Are Side Effects Associated with Using Lactulose?"

Long-Term Effects

  • See "What Are Side Effects Associated with Using Lactulose?"


  • Diabetes (preparation contains lactose and galactose)
  • Monitor for electrolyte imbalance when drug is used for longer than 6 months or in patients predisposed to electrolyte abnormalities
  • Avoid using other laxatives concomitantly
  • Inadequate response possible when taken concomitantly with anti-infective

Pregnancy and Lactation

  • Lactulose use during pregnancy may be acceptable. Either animal studies show no risk, or human studies are not available or animal studies showed minor risks and human studies were done and showed no risk
  • It is unknown if lactulose is distributed into breast milk; use with caution

Medscape. Lactulose.

Medically Reviewed by a Doctor on 5/15/2017

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