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Lidocaine

Medical and Pharmacy Editor:

Brand Name: Lidocaine CV, Lidopen

Generic Name: Lidocaine

Drug Class: Antidysrhythmics

What Is Lidocaine and How Does It Work?

Lidocaine is used to relieve nerve pain after shingles (infection with the herpes zoster virus). This type of pain is called post-herpetic neuralgia. Lidocaine helps to reduce sharp/burning/aching pain as well as discomfort caused by skin areas that are overly sensitive to touch. Lidocaine belongs to a class of drugs known as local anesthetics. It works by causing a temporary loss of feeling in the area where you apply the patch.

Lidocaine is available under the following different brand names: Lidocaine CV, and Lidopen.

Dosage of Lidocaine:

Adult and Pediatric Dosage Forms and Strengths

Infusion solution in D5W

  • 100 mg/100mL
  • 200 mg/100mL
  • 400 mg/100mL
  • 800 mg/100mL

Injectable solution

  • 10 mg/100mL
  • 20 mg/100mL

Dosing Consideraations – Should be Given as Follows:

Ventricular Arrhythmias

Adult

  • 1-1.5 mg/kg slow intravenous (IV) bolus over 2-3 minutes
  • May repeat doses of 0.5-0.75 mg/kg in 5-10 minutes up to 3 mg/kg total
  • Continuous infusion: 1-4 mg/min intravenously (IV)
  • If IV not feasible may use intraosseous infusion (IO) or via endotracheal tube (ET)
  • Monitor: ECG

Pediatric

  • Bolus: 0.5-1 mg/kg IV/IO/ET, not to exceed 100 mg; follow with continuous infusion; if delay between bolus and start of infusion is more than 15 minutes, administer a second bolus every
  • 5-10 minutes to 5 mg/kg, THEN
  • Continuous infusion: 20-50 mcg/kg/min intravenous (IV)
  • Monitor ECG

Regional Anesthesia (IV)

  • 4 mg/kg

Paracervical Block

  • 200 mg per 90 minutes in obstetric and non-obstetric patients

Other Indications and Uses

What Are Side Effects Associated with Using Lidocaine?

Common Side effects of Lidocaine include:

Serious side effects of lidocaine include:

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

What Other Drugs Interact with Lidocaine?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

Severe Interactions of lidocaine include:

Serious Interactions of lidocaine include:

  • axitinib
  • bosutinib
  • cobimetinib
  • eliglustat
  • fentanyl
  • fentanyl intranasal
  • fentanyl iontophoretic transdermal system
  • fentanyl transdermal
  • fentanyl transmucosal
  • fluvoxamine
  • fosamprenavir
  • ivabradine
  • ivacaftor
  • mefloquine
  • naloxegol
  • olaparib
  • pefloxacin
  • phenytoin
  • pimozide
  • pomalidomide

Lidocaine has moderate interactions with at least 62 different drugs.

Lidocaine has mild interactions with at least 28 different drugs.

This information does not contain all possible interactions or adverse effects. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns or for more information about this medicine.

What Are Warnings and Precautions for Lidocaine?

Warnings

  • This medication contains lidocaine
  • Do not take Lidocaine CV or Lidopen if you are allergic to lidocaine or any ingredients contained in this drug
  • Keep out of reach of children
  • In case of overdose, get medical help or contact a Poison Control Center immediately

Contraindications

Effects of Drug Abuse

  • No information available

Short-Term Effects

  • See "What Are Side Effects Associated with Using Lidocaine?"

Long-Term Effects

  • See "What Are Side Effects Associated with Using Lidocaine?"

Cautions

Pregnancy and Lactation

  • Lidocaine may be acceptable to use during pregnancy
  • Either animal studies show no risk but human studies are not available or animal studies showed minor risks and human studies done and showed no risk
  • Lidocaine crosses into breast milk; use caution if breastfeeding
Reviewed on 5/31/2017

Medscape. Lidocaine.
https://reference.medscape.com/drug/lidocaine-cv-lidopen-342302

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