Flavocoxid/Citrated Zinc Bisglycinate

Reviewed on 9/16/2021

Brand Name: Limbrel
Generic Name: Flavocoxid/Citrated Zinc Bisglycinate
Drug Class: Nutritionals, Other; Anti-Inflammatory Agents

What Is Flavocoxid/Citrated Zinc Bisglycinate and How Does It Work?

Flavocoxid/citrated zinc bisglycinate is used for the clinical dietary management of the metabolic processes of osteoarthritis.

  • Flavocoxid/citrated zinc bisglycinate is available under the following different brand names: Limbrel.

What Are Dosages of Flavocoxid/Citrated Zinc Bisglycinate?

Dosages of Flavocoxid/Citrated Zinc Bisglycinate:

Dosage Forms and Strengths

Capsule

  • 250mg
  • 500mg
Dosage Considerations – Should be Given as Follows:

Osteoarthritis

  • Medical food product indicated for the clinical dietary management of the metabolic processes of osteoarthritis
  • 250-500 mg orally every 12 hours
Administration
  • May take with or without food
  • Increased absorption if taken 1 hour before or after meals
  • Taking with food does not affect metabolism and may buffer effects of slight indigestion

Safety and efficacy not established in pediatric patients

QUESTION

What joints are most often affected by osteoarthritis? See Answer

What Are Side Effects Associated with Using Flavocoxid/Citrated Zinc Bisglycinate?

Side effects of flavocoxid/citrated zinc bisglycinate include:

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

What Other Drugs Interact with Flavocoxid/Citrated Zinc Bisglycinate?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first.

  • Flavocoxid/citrated zinc bisglycinate has no listed severe interactions with other drugs.
  • Flavocoxid/citrated zinc bisglycinate has no listed serious interactions with other drugs.
  • Flavocoxid/citrated zinc bisglycinate has no listed moderate interactions with other drugs.
  • Flavocoxid/citrated zinc bisglycinate has no listed mild interactions with other drugs.
     

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.

What Are Warnings and Precautions for Flavocoxid/Citrated Zinc Bisglycinate? 

Warnings
 

This medication contains flavocoxid/citrated zinc bisglycinate. Do not take Limbrel if you are allergic to flavocoxid/citrated zinc bisglycinate or any ingredients contained in this drug.


Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.

Contraindications

  • Hypersensitivity to any component of flavocoxid or to flavonoids; foods rich in flavonoid contents include colored fruits and vegetables, dark chocolate, tea (especially green tea), red wine, and Brazil nuts

Effects of Drug Abuse

  • No information available

Short-Term Effects

  • See "What Are Side Effects Associated with Using Flavocoxid/Citrated Zinc Bisglycinate?”

Long-Term Effects

  • See "What Are Side Effects Associated with Using Flavocoxid/Citrated Zinc Bisglycinate?”

Cautions

  • Borderline elevations (1.2-3 times ULN) of 1 or more liver tests without other signs or symptoms occurred in controlled clinical trials in less than 10% of subjects; notable elevations of ALT and AST (approximately greater than 3 to 5 times ULN) occurred in controlled clinical trials in less than 2% of subjects
  • Hypersensitivity pneumonitis (rare reports)
  • Use caution in patients with a history of gastrointestinal disorders
  • Use only under close supervision of a healthcare professional
  • Cases of serious adverse events, including drug-induced liver injury and hypersensitivity pneumonitis, involving flavocoxid/citrated zinc bisglycinate; advise patients to immediately discontinue treatment; if patients experience any symptoms or other health problems while taking flavocoxid/citrated zinc bisglycinate, the FDA encourages you to work with them to provide clinical information through MedWatch

Pregnancy and Lactation

  • Flavocoxid/citrated zinc bisglycinate has not been studied in pregnant women. Flavocoxid/citrated zinc bisglycinate is not recommended for use during pregnancy.
  • It is unknown if flavocoxid/citrated zinc bisglycinate is excreted in breast milk. Flavocoxid/citrated zinc bisglycinate  is not recommended while breastfeeding.

SLIDESHOW

Slideshow: Exercises for Knee Osteoarthritis and Joint Pain See Slideshow

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References
https://reference.medscape.com/drug/limbrel-flavocoxid-citrated-zinc-bisglycinate-999684

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