Reviewed on 8/25/2021

What Is Lycopene and How Does It Work?

Lycopene suggested uses include for cancer, preventing atherosclerosis, cardiovascular disease, prostate cancer, human papillomavirus (HPV) infection, cataracts, asthma, antioxidant, and as an anti-inflammatory.

There is no association between lycopene and the risk of bladder and colon cancers.

There are conflicting studies on use of lycopene for cardiovascular disease. More studies are needed to determine effectiveness.

There is insufficient information about effectiveness of lycopene for atherosclerosis.

Preliminary evidence suggests a significant clinical response with use of lycopene for oral leukoplakia.

Evidence suggests lycopene may reduce the risk of ovarian, pancreatic, prostate, and lung cancers.

Research suggests that women with higher levels of lycopene cleared oncogenic HPV in an average of 8.5 months compared to 11-12 months in women with lower levels.

Lycopene is available under the following different brand and other names: all-trans lycopene, psi-carotene, psi-psi-carotene, and solanrubin.

Dosages of Lycopene

Suggested Dosing

General Dosing Guidelines

  • Pure compound: 13-75 mg/day orally
  • Capsule: 10-30 mg twice daily orally

Dosage Considerations – Should be Given as Follows:

Prostate Cancer

  • 15 mg twice daily orally

Oral Leukoplakia

  • 4-8 mg/day orally
  • Specific lycopene supplement (LycoRed)

Preventing Exercise-induced Asthma

  • 30 mg/day orally


Skin Cancer Symptoms, Types, Images See Slideshow

What Are Side Effects Associated with Using Lycopene?

Lycopene has no reported side effects.

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

What Other Drugs Interact with Lycopene?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

Lycopene has no known severe interactions with other drugs.

Lycopene has no known serious interactions with other drugs.

Lycopene has no known moderate interactions with other drugs.

Lycopene has no known mild interactions with other drugs.

This information does not contain all possible interactions or adverse effects. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns or for more information about this medicine.

What Are Warnings and Precautions for Lycopene?


This medication contains lycopene. Do not take all-trans lycopene, psi-carotene, psi-psi-carotene, or solanrubin if you are allergic to lycopene or any ingredients contained in this drug.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.


  • None reported

Effects of Drug Abuse

  • None

Short-Term Effects

  • See "What Are Side Effects Associated with Using Lycopene?"

Long-Term Effects

  • See "What Are Side Effects Associated with Using Lycopene?"


  • None

Pregnancy and Lactation

  • Avoid use of lycopene during pregnancy or while breastfeeding.
Medscape. Lycopene.

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