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Magnesium Citrate

  • Medical and Pharmacy Editor: John P. Cunha, DO, FACOEP
    John P. Cunha, DO, FACOEP

    John P. Cunha, DO, FACOEP

    John P. Cunha, DO, is a U.S. board-certified Emergency Medicine Physician. Dr. Cunha's educational background includes a BS in Biology from Rutgers, the State University of New Jersey, and a DO from the Kansas City University of Medicine and Biosciences in Kansas City, MO. He completed residency training in Emergency Medicine at Newark Beth Israel Medical Center in Newark, New Jersey.

Brand Name: N/A

Generic Name: Magnesium Citrate

Drug Class: Laxatives, Saline

What Is Magnesium Citrate and How Does It Work?

Magnesium Citrate is an over-the-counter (OTC) medication that can be used as a nutritional supplement or for treatment of acid indigestion and constipation.

Dosage of Magnesium Citrate:

Adult and Pediatric Dosages:

Liquid

  • 290 mg/5ml

Tablet

  • 100 mg (elemental)

Dosing Considerations – Should be Given as Follows:

Nutritional Supplementation

19-30 year old:

  • Men – 400 mg/day
  • Women – 310 mg/day
  • Pregnant women younger than 50 years old: 350 mg/day
  • Breastfeeding women younger than 50 years old: 320 mg/day

Over 30 years old:

  • Men – 420 mg/day
  • Women – 320 mg/day
  • Pregnant women younger than 50 years old: 360 mg/day
  • Breastfeeding women younger than 50 years old: 320 mg/day

Constipation/Bowel Evacuation:

Adult dosage:

  • 195-300 ml orally in a single daily dose or in divided doses with a full glass of water
  • Alternatively, 2-4 tablets orally at bedtime

Pediatric dosage:

  • Children under 2 years old: Safety and efficacy not established
  • Children 2-6 years old: 60-90 ml orally once or in divided doses, not to exceed 90 mg/24 hours
  • Children 6-12 years old: 90-120 ml in a single dose or divided doses with a full glass of water
  • Children over 12 years old: 195-300 ml orally in a single dose or in divided doses with a full glass of water, alternatively, may administer 2-4 tablets orally at bedtime

Acid Indigestion:

  • 1 tablet twice daily or as directed by healthcare provider

What Are Side Effects Associated with Using Magnesium Citrate?

Common Side effects of Magnesium Citrate include:

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

What Other Drugs Interact with Magnesium Citrate?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

Magnesium Citrate has no known severe interactions with any drugs.

Serious Interactions of Magnesium Citrate include:

Moderate Interactions of Magnesium Citrate include:

Magnesium Citrate has mild interactions with at least 44 different drugs.

This information does not contain all possible interactions or adverse effects. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns or for more information about this medicine.

What Are Warnings and Precautions for Magnesium Citrate?

Warnings

Avoid use when on a low sodium diet.

Magnesium citrate is only intended for occasional use in treatment of constipation.

Avoid use when the following conditions are present:

Use with caution in patients with abnormal muscle weakness (myasthenia gravis) or other neuromuscular disease.

This medication contains magnesium citrate. Do not take it if you are allergic to magnesium citrate or any ingredients contained in this drug.

  • Keep out of reach of children
  • In case of overdose, get medical help or contact a Poison Control Center immediately

Contraindications

  • Avoid use when on a low sodium diet

Effects of Drug Abuse

  • None

Short-Term Effects

  • See "What Are Side Effects Associated with Using Magnesium Citrate?"

Long-Term Effects

  • See "What Are Side Effects Associated with Using Magnesium Citrate?"

Cautions

Use caution in renal insufficiency or magnesium-restricted diet.

For occasional use only in treatment of constipation.

Use with caution in patients with abnormal muscle weakness (myasthenia gravis) or other neuromuscular disease.

Should be refrigerated to maintain potency and palatability.

Avoid use when the following conditions are present:

  • renal failure
  • existing electrolyte imbalance
  • appendicitis or acute surgical abdomen
  • myocardial damage or heart block
  • fecal impaction or rectal fissures
  • intestinal obstruction or perforation
  • dehydration

Pregnancy and Lactation

  • Magnesium citrate use in pregnancy is generally acceptable
  • Controlled studies in pregnant women show no evidence of fetal risk
  • Use of magnesium citrate when breastfeeding appears to be safe

Medscape. Magnesium Citrate.
https://reference.medscape.com/drug/magnesium-citrate-342017#0

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