Erythromycin Base, Sulfisoxazole

Reviewed on 8/9/2021

Brand Name: Pediazole

Generic Name: Erythromycin Base/Sulfisoxazole

Drug Class: Sulfonamides

What Is Erythromycin Base/Sulfisoxazole Used For and How Does it Work?

Erythromycin base/sulfisoxazole is used to treat H. influenzae acute otitis media.

Erythromycin base/sulfisoxazole is available under the following different brand names: Pediazole.

What Are the Dosages of Erythromycin Base/Sulfisoxazole?

Dosage Forms and Strengths

Oral Suspension

  • (200mg/600mg)/5mL

Dosage Considerations – Should be Given as Follows:

H. influenzae Acute Otitis Media

  • Children over 2 months: 50 mg/kg/day (erythromycin) or 150 mg/kg/day (sulfisoxazole) orally divided every 6-8 hours for 10 days
  • Children under 2 months: Contraindicated
  • Not to exceed 6 g/day sulfisoxazole
  • Not prescribed for adults

QUESTION

Ear infection or acute otitis media is an infection of the middle ear. See Answer

What Are Side Effects Associated with Using Erythromycin Base/Sulfisoxazole?

Side effects of Erythromycin Base/Sulfisoxazole include:

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

What Other Drugs Interact with Erythromycin Base/Sulfisoxazole?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

Erythromycin Base/Sulfisoxazole has no listed severe interactions with other drugs.

Erythromycin Base/Sulfisoxazole has no listed serious interactions with other drugs.

Erythromycin Base/Sulfisoxazole has no listed moderate interactions with other drugs.

Erythromycin Base/Sulfisoxazole has no listed mild interactions with other drugs.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.

What Are Warnings and Precautions for Erythromycin Base/Sulfisoxazole?

Warnings

This medication contains erythromycin base/sulfisoxazole. Do not take Pediazole if you are allergic to erythromycin base/sulfisoxazole or any ingredients contained in this drug.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.

Contraindications

Effects of Drug Abuse

  • No information is available.

Short-Term Effects

  • See "What Are Side Effects Associated with Using Erythromycin Base/Sulfisoxazole?"

Long-Term Effects

  • See "What Are Side Effects Associated with Using Erythromycin Base/Sulfisoxazole?"

Cautions

  • No information is available.

Pregnancy and Lactation

Erythromycin base/sulfisoxazole is not prescribed for adults and is unlikely to be used by pregnant or breastfeeding women.

Use erythromycin base/sulfisoxazole with caution during pregnancy if the benefits outweigh the risks. Animal studies show risk and human studies are not available or neither animal nor human studies were done.

Erythromycin base/sulfisoxazole enters breast milk. Consult your doctor before breastfeeding.

SLIDESHOW

Ear Infection Symptoms, Causes, and Treatment See Slideshow
References
https://reference.medscape.com/drug/pediazole-erythromycin-base-sulfisoxazole-342546

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