Stibogluconate Sodium

Reviewed on 2/18/2020

Brand Name and Other Names: Pentostam, stibogluconate sodium

Generic Name: Sodium Stibogluconate

Drug Class: Antileishmaniasis Agents

What Is Sodium Stibogluconate Used For and How Does it Work?

Sodium stibogluconate has orphan designation for use to treat leishmaniasis and acute myeloid leukemia (AML).

Sodium stibogluconate is available in the United States only from the Centers for Disease Control (CDC).

Sodium stibogluconate is available under the following different brand names: Pentostam and stibogluconate sodium.

Dosages of Sodium Stibogluconate:

Injectable Solution

  • 100mg Sb/mL

Dosage Considerations – Should be Given as Follows:

Leishmaniasis (Orphan)

  • 20 mg Sb/kg/day (maximum 850 mg) IV/IM for 20-28 days
  • Available in the United States only from CDC

Acute Myeloid Leukemia (Orphan)

SLIDESHOW

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What Are Side Effects Associated with Using Sodium Stibogluconate?

Common side effects of sodium_stibogluconate include:

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

What Other Drugs Interact with Sodium Stibogluconate?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

Sodium Stibogluconatehas no listed severe interactions with other drugs.

Sodium Stibogluconatehas no listed serious interactions with other drugs.

Sodium Stibogluconatehas moderate interactions with at least 71 different drugs.

Sodium Stibogluconatehas mild interactions with at least 101 different drugs.

What Are Warnings and Precautions for Sodium Stibogluconate?

Warnings

This medication contains sodium stibogluconate. Do not take Pentostam or stibogluconate sodium if you are allergic to sodium stibogluconate or any ingredients contained in this drug.

Contraindications

Effects of Drug Abuse

  • No information available.

Short-Term Effects

  • See "What Are Side Effects Associated with Using Sodium Stibogluconate?"

Long-Term Effects

  • See "What Are Side Effects Associated with Using Sodium Stibogluconate?"

Cautions

  • No information available.

Pregnancy and Lactation

No information is available regarding use of sodium stibogluconate during pregnancy or while breastfeeding. Consult your doctor.

QUESTION

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References
https://reference.medscape.com/drug/pentostam-stibogluconate-sodium-342669

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