What Is Phosphatidylserine and How Does It Work?
Phosphatidylserine is an herbal supplement used to treat conditions such as depression, and mental impairment in geriatric and Attention Deficit Hyperactivity Disorder.
Trials show benefit in memory impairment and dementia. Phosphatidylserine may lose its effectiveness with extended use over 16 weeks.
Dosage of Phosphatidylserine
Alzheimer's Disease
- 100 mg orally three times daily
Senile Dementia and Cognitive/Memory Impairment
- 100 mg orally three times daily
Attention Deficit Hyperactivity Disorder in Children
- 200-300 mg orally daily
Dosing Consideraations – Should be Given as Follows:
- None

QUESTION
Laughter feels good because… See AnswerWhat Are Side Effects Associated with Using Phosphatidylserine?
Phosphatidylserine has no reported side effects.
This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.
What Other Drugs Interact with Phosphatidylserine?
If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.
- Phosphatidylserine has no known severe interactions with other drugs.
- Phosphatidylserine has no known serious interactions with other drugs.
- Phosphatidylserine has no known moderate interactions with other drugs.
- Phosphatidylserine has no known mild interactions with other drugs.
This information does not contain all possible interactions or adverse effects. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns or for more information about this medicine.
What Are Warnings and Precautions for Phosphatidylserine?
Warnings
None.
This medication contains phosphatidylserine. Do not take it if you are allergic to phosphatidylserine or any ingredients contained in this drug.
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately
Contraindications
- None
Effects of Drug Abuse
- No information available
Short-Term Effects
- See "What Are Side Effects Associated with Using Phosphatidylserine?"
Long-Term Effects
- See "What Are Side Effects Associated with Using Phosphatidylserine?"
Cautions
- None
Pregnancy and Lactation
- There is no information available about use of phosphatidylserine during pregnancy or if breastfeeding. Consult your doctor.

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https://reference.medscape.com/drug/phosphatidylserine-344547