Brand Name: Accupril
Generic Name: Quinapril
Drug Class: ACE Inhibitors
What Is Accupril and How Does It Work?
Quinapril is an angiotensin converting enzyme (ACE) inhibitor used for treating high blood pressure and heart failure.
Quinapril is available under the following different brand names: Accupril.
Dosages of Accupril:
Adult and Pediatric Dosage Forms and Strengths
- 5 mg
- 10 mg
- 20 mg
- 40 mg
Dosage Considerations – Should be Given as Follows:
- Adult, initial: 10-20 mg orally once/day; may administer 5 mg in patients receiving diuretic therapy if the diuretic is continued
- Adult, maintenance: 20-80 mg orally once/day or divided every 12 hours
- Pediatric, off-label: 5-10 mg orally once/day initially
- Dose adjustment not necessary
Congestive Heart Failure
- Initial: 5 mg orally every 12 hours
- Maintenance: 20-40 mg orally once/day or divided every 12 hours
Diabetic Nephropathy (Off-Label)
- Slows rate of progression of renal disease in patients with hypertension, diabetes mellitus, and microalbuminuria
- Initial: 10-20 mg orally once/day
- Maintenance: 20-80 mg orally once/day or divided every 12 hours
Renal impairment with hypertension
- CrCl greater than 60 mL/minute: 10 mg/day
- CrCl 30-60 mL/minute: 5 mg/day
- CrCl 10-30 mL/minute: 2.5 mg/day
- CrCl less than 10 mL/minute: Insufficient data
Renal impairment with congestive heart failure (CHF)
Geriatric: 2.5-5 mg/day initially; increase dose by increments of 2.5-5 mg at 1-2 week intervals; adjust for renal impairment
Get tips on handling your hypertension.