Pyrethrins/Piperonyl Butoxide

Reviewed on 8/23/2021

What Is Pyrethrins/Piperonyl Butoxide and How Does It Work?

Pyrethrins/piperonyl butoxide is an over-the-counter (OTC) product used for the treatment of head, body, and pubic lice.

Pyrethrins/piperonyl butoxide is available under the following different brand names: RID Shampoo, Klout Shampoo, Pronto Shampoo, RID Mousse, A-200 Shampoo, Tisit Gel, Tisit Lotion, and Tisit Shampoo.

What Are the Dosages of Pyrethrins/Piperonyl Butoxide?

Dosages of Pyrethrins/Piperonyl Butoxide:

Dosage Forms and Strengths

Lotion

  • 0.3%/2%

Gel

  • 0.3%/3%

Shampoo

  • 0.33%/4%

Dosage Considerations – Should be Given as Follows:

Treatment of Head, Body, Pubic Lice

  • Apply to completely wet infested areas, leave on 10 minutes and wash with a large amount of warm water
  • Use a fine-toothed comb to remove lice and egg from hair
  • Shampoo hair to restore body and luster
  • Do not exceed 2 consecutive applications within 24 hours
  • Retreat in 7-10 days
  • Amount to apply varies: See package insert

What Are Side Effects Associated with Using Pyrethrins/Piperonyl Butoxide?

Side effects of pyrethrins/piperonyl butoxide include:

  • Redness
  • Itching
  • Burning
  • Stinging
  • Hives
  • Swelling (edema)
  • Slight corneal erosion

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

What Other Drugs Interact with Pyrethrins/Piperonyl Butoxide?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

  • Pyrethrins/piperonyl butoxide has no listed severe interactions with other drugs.
  • Pyrethrins/piperonyl butoxide has no listed serious interactions with other drugs.
  • Pyrethrins/piperonyl butoxide has no listed moderate interactions with other drugs.
  • Pyrethrins/piperonyl butoxide has no listed mild interactions with other drugs.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.

QUESTION

Ringworm is caused by a fungus. See Answer

What Are Warnings and Precautions for Pyrethrins/Piperonyl Butoxide? 

Warnings

  • This medication contains pyrethrins/piperonyl butoxide. Do not take RID Shampoo, Klout Shampoo, Pronto Shampoo, RID Mousse, A-200 Shampoo, Tisit Gel, Tisit Lotion, or Tisit Shampoo if you are allergic to pyrethrins/piperonyl butoxide or any ingredients contained in this drug.
  • Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.

Contraindications

  • Hypersensitivity to product, ragweed (Asteraceae family plants) hypersensitivity

Effects of Drug Abuse

  • No information is available

Short-Term Effects

  • See "What Are Side Effects Associated with Using Pyrethrins/Piperonyl Butoxide?”

Long-Term Effects

  • See "What Are Side Effects Associated with Using Pyrethrins/Piperonyl Butoxide?”

Cautions

  • For external use only
  • Avoid using near-eye or use in eyelashes or eyebrow
  • Avoid contact with mucosal tissues (oral, nasal, genitalia)

Pregnancy and Lactation

  • Use pyrethrins/piperonyl butoxide with caution during pregnancy if the benefits outweigh the risks. Animal studies show risk and human studies are not available or neither animal nor human studies were done.
  • Lactating women may receive pyrethrins/piperonyl butoxide therapy. Consult your doctor before breastfeeding.
References
https://reference.medscape.com/drug/rid-klout-shampoo-pyrethrins-piperonyl-butoxide-topical-343499

Health Solutions From Our Sponsors