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Sorbitol

Medical and Pharmacy Editor:

Brand Name: N/A

Generic Name: Sorbitol

Drug Class: Laxatives, Osmotic

What Is Sorbitol and How Does It Work?

Sorbitol is used to relieve occasional constipation and irregularity. Sorbitol generally produces bowel movement in 1/4 to 1 hour when used rectally.

Sorbitol is also used as a pharmaceutical aide (sweetener).

For other uses of sorbitol, ask your doctor.

Dosages of Sorbitol:

Adult and Pediatric Dosage Forms and Strengths

Irrigation solution

  • 3 g/100mL (3%)

Oral solution

  • 70%

Dosage Considerations – Should be Given as Follows:

Constipation

  • Adult, Oral: 30-150 mL (70% solution) once
  • Adult, Rectal enema: 120 mL of 25-30% solution once
  • Children under 2 years: Safety and efficacy not established
  • Children 2-11 years:
    • Oral: 2 mL/kg (as 70% solution) once
    • Rectal enema: 30-60 mL as 25-30% solution
  • Children 12 years and older:
    • Oral: 30-150 mL (70% solution) once
    • Rectal enema: 120 mL of 25-30% solution once

Sodium Polystyrene Sulfonate Adjunct

  • Adult: 15 mL of 70% solution or 10-20 mL/2 hours orally until diarrhea occurs
  • Children under 12 years: Safety and efficacy not established
  • Children 12 years and older: 15 mL of 70% solution or 10-20 mL/2 hours orally until diarrhea occurs

Transurethral Surgical Procedures

  • 3-3.3% as surgical procedure irrigation

What Are Side Effects Associated with Using Sorbitol?

Common side effects of sorbitol include:

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

What Other Drugs Interact with Sorbitol?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

Sorbitol has no known severe interactions with other drugs.

Serious Interactions of sorbitol include:

  • sodium polystyrene sulfonate

Moderate Interactions of sorbitol include:

  • deflazacort
  • dichlorphenamide

Sorbitol has no known mild interactions with other drugs.

This information does not contain all possible interactions or adverse effects. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns or for more information about this medicine.

What Are Warnings and Precautions for Sorbitol?

Warnings

This medication contains sorbitol. Do not take sorbitol if you are allergic to sorbitol or any ingredients contained in this drug.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.

Contraindications

Effects of Drug Abuse

  • No information available

Short-Term Effects

  • See "What Are Side Effects Associated with Using Sorbitol?"

Long-Term Effects

  • See "What Are Side Effects Associated with Using Sorbitol?"

Cautions

  • Patients with severe cardiopulmonary or renal impairment.
  • Dehydration, electrolyte abnormalities.
  • Patients unable to metabolize sorbitol.

Pregnancy and Lactation

  • Use sorbitol with caution during pregnancy if benefits outweigh risks. Animal studies show risk and human studies are not available or neither animal nor human studies were done.
  • Use caution with use of sorbitol if breastfeeding. Consult your doctor.
Reviewed on 8/22/2017

Medscape. Sorbitol.
https://reference.medscape.com/drug/sorbitol-342033
DailyMed. Sorbitol.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=16cc9d47-5382-4237-ab84-f22c5436fe2e

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