In this Article
- What Is Trimethoprim and How Does It Work?
- What Are Side Effects Associated with Using Trimethoprim?
- What Other Drugs Interact with Trimethoprim?
- What Are Warnings and Precautions for Trimethoprim?
What Are Side Effects Associated with Using Trimethoprim?
Common side effects of trimethoprim include:
- Aseptic meningitis
- BUN and creatinine increased
- Changes in taste
- Cholestatic jaundice
- Erythema multiforme
- Exfoliative dermatitis
- High blood potassium (hyperkalemia)
- Hypersensitivity reactions
- Itching (common)
- Liver enzyme elevation
- Loss of appetite
- Low blood platelet count (thrombocytopenia)
- Low blood sodium (hyponatremia)
- Low white blood cell count (leukopenia, neutropenia)
- Maculopapular rash (3-7% at 200 mg/day; incidence higher with larger daily doses)
- Megaloblastic anemia
- Phototoxic skin eruptions
- Severe allergic reaction (anaphylaxis)
- Skin sensitivity to sunlight
- Stevens-Johnson syndrome
- Stomach pain or upset
- Swollen tongue
- Toxic epidermal necrolysis
This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.
Medically Reviewed by a Doctor on 6/15/2017
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