Brand Name: Primsol, Proloprim, TMP
Generic Name: Trimethoprim
Drug Class: Antibiotics, Other
What Is Trimethoprim and How Does It Work?
Trimethoprim treats only bacterial infections. It will not work for viral infections (e.g., common cold, flu). Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness.
Trimethoprim is available under the following different brand names: Primsol, Proloprim, and TMP.
Dosages of Trimethoprim:
Dosage Forms and Strengths
- 50 mg/5mL
- 100 mg
Dosage Considerations – Should be Given as Follows:
- 100 mg orally every 12 hours
- CrCl 15-30 mL/min: 50 mg every 12 hours
- CrCl less than 15 mL/min: 100 mg every 24 hours or avoid use
- See also combo with sulfamethoxazole (Cotrim/Bactrim/Septra/Sulfatrim)
- Available also as a combo with sulfadiazine (Coptin) in Canada
Other Indications and Uses
- Urinary tract infection (UTI) caused by E. coli, Enterobacter spp., K. pneumoniae, P. mirabilis, coagulase-negative Staphylococcus spp
- Pediatric: Children under 12 years old: safety and efficacy not established
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