Trifluridine Ophthalmic

Reviewed on 8/20/2021

Brand Name and Other Names: Viroptic

Generic Name: Trifluridine Ophthalmic

Drug Class: Antivirals, Ophthalmic

What Is Trifluridine Ophthalmic Used For and How Does it Work?

Trifluridine ophthalmic is used to treat primary keratoconjunctivitis and recurrent epithelial keratitis due to herpes simplex virus types 1 and 2.

Trifluridine ophthalmic is available under the following different brand names: Viroptic.

What Are the Dosages of Trifluridine Ophthalmic?

Dosages of Trifluridine Ophthalmic:

Dosage Forms and Strengths

Ophthalmic Solution

  • 1%

Dosage Considerations – Should be Given as Follows:

Herpes Simplex Virus

  • Indicated for the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to herpes simplex virus, types 1 and 2
  • Adults and children 6 years and older: 1 drop onto cornea every 2 hours while awake until re-epithelialization (not to exceed 9 drops/day), THEN
  • 1 drop every 4 hours (minimum 5 drops/day) for 7 days
  • Not to exceed treatment beyond 21 days
  • Children under 6 years: Safety and efficacy not established

Other Indications & Uses

  • Herpes simplex virus keratitis and keratoconjunctivitis
  • Centers for Disease Control (CDC) recommends for accidental smallpox virus ophthalmic infections

SLIDESHOW

Pink Eye (Conjunctivitis) Symptoms, Causes, Treatments See Slideshow

What Are Side Effects Associated with Using Trifluridine Ophthalmic?

Common side effects of trifluridine_ophthalmic include:

  • Transient burning/stinging
  • Eyelid swelling

Other side effects of trifluridine ophthalmic include:

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

What Other Drugs Interact with Trifluridine Ophthalmic?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

  • Trifluridine ophthalmic has no listed severe interactions with other drugs.
  • Trifluridine ophthalmic has no listed serious interactions with other drugs.
  • Trifluridine ophthalmic has no listed moderate interactions with other drugs.
  • Trifluridine ophthalmic has no listed mild interactions with other drugs.

What Are Warnings and Precautions for Trifluridine Ophthalmic?

Warnings

This medication contains trifluridine ophthalmic. Do not take Viroptic if you are allergic to trifluridine ophthalmic or any ingredients contained in this drug.

Contraindications

  • Hypersensitivity

Effects of Drug Abuse

  • No information is available.

Short-Term Effects

  • See "What Are Side Effects Associated with Using Trifluridine Ophthalmic?"

Long-Term Effects

  • See "What Are Side Effects Associated with Using Trifluridine Ophthalmic?"

Cautions

  • Consider other treatments if no improvement after 7 days or incomplete re-epithelialization after 14 days
  • Use for more than 21 days should be avoided because of potential ocular toxicity
  • Inactive against bacteria, fungi, and chlamydia

Pregnancy and Lactation

Use trifluridine ophthalmic with caution during pregnancy if the benefits outweigh the risks. Animal studies show risk and human studies are not available or neither animal nor human studies were done.

Trifluridine ophthalmic is unlikely to be distributed into breast milk. Use caution while breastfeeding.

QUESTION

What causes dry eyes? See Answer
References
https://reference.medscape.com/drug/viroptic-trifluridine-ophthalmic-343587

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