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Vitamin D

Medical and Pharmacy Editor:

Brand Name: Drisdol, Calciferol

Generic Name: vitamin D, cholecalciferol, 1,25-Dihydroxycholecalciferol, ergocalciferol

Drug Class: Vitamins, Fat-Soluble

What Is Vitamin D and How Does It Work?

Vitamin D is a fat-soluble vitamin indicated for use in the treatment of hypoparathyroidism, refractory rickets, also known as vitamin D resistant rickets, and familial hypophosphatemia.

Vitamin D is available under the following different brand names: Drisdol, Calciferol, cholecalciferol, 1,25-Dihydroxycholecalciferol, and ergocalciferol.

Dosages of Vitamin D Should Be Given As Follows:

Adult and Pediatric Dosage Forms & Strengths

1 mcg = 40 international units (IU)

Oral Solution

  • 8000IU/mL (200mcg/mL)
Capsule
  • 50,000IU (1.25mg)
Tablet
  • 400IU (10mcg)
  • 2000IU (50mcg)

Dosage Considerations

Vitamin D toxicity may last 2 months or more after therapy is discontinued.

Adequate clinical response to vitamin D therapy is dependent on adequate dietary calcium.

In patients with rickets, the range between therapeutic and toxic doses is narrow in vitamin D–resistant patients; adjust dose based on clinical response to avoid toxicity.

Vitamin D as Nutritional Supplementation

Recommended daily allowance (RDA)

19-70 years: 600 IU (15 mcg)/day

Pregnant or lactating women: 600 IU (15 mcg)/day

Vitamin D as Nutritional Supplementation

Recommended daily allowance (RDA)

19-70 years: 600 IU (15 mcg)/day

Pregnant or lactating women: 600 IU (15 mcg)/day

Vitamin D to Prevent and Treat Osteoporosis

>50 years: 800-1000 IU (20-25 mcg) PO once daily with calcium supplements

Vitamin D to Prevent and Treat Hypoparathyroidism

50,000-200,000 IU (0.625-5 mg) PO once daily with calcium supplements

Vitamin D to Prevent and Treat Vitamin D-Resistant Rickets

12,000-500,000 IU (0.3-12.5 mg) PO once daily

Vitamin D to Prevent and Treat Familial Hypophosphatemia

10,000-60,000 IU (0.25-1.5 mg) PO once daily with phosphate supplements

Medically Reviewed by a Doctor on 2/16/2017



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