Medical Editor: John P. Cunha, DO, FACOEP Last updated on RxList: 12/13/2021
Copper Side Effects Center

What Is Copper?

Copper (cupric chloride injection) is an additive to intravenous solutions for total parenteral nutrition (TPN) is indicated for use as a supplement to intravenous solutions given for total parenteral nutrition (TPN). Administration helps to maintain copper serum levels and to prevent depletion of endogenous stores and subsequent deficiency symptoms.

What Are Side Effects of Copper?

Copper has no known side effects.

Dosage for Copper

For the adult receiving TPN, the suggested additive dosage of copper is 0.5 to 1.5 mg copper/day (1.25 to 3.75 mL/day). For pediatric patients, the suggested additive dosage of copper is 20 mcg copper/kg/day (0.05 mL/kg/day).

What Drugs, Substances, or Supplements Interact with Copper?

Copper may interact with ascorbic acid in total parenteral nutrition solutions.

Copper During Pregnancy or Breastfeeding

Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using copper; it is unknown how it would affect a fetus. It is unknown if copper passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Copper (cupric chloride injection) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Next to red peppers, you can get the most vitamin C from ________________. See Answer
Copper Professional Information


None known.


Cupric ion may degrade ascorbic acid in total parenteral nutrition (TPN) solutions. In order to avoid this loss of ascorbate, multivitamin additives should be added to TPN solutions immediately prior to infusion. Alternatively, the multivitamin additive may be added to one container of TPN solution, followed by copper in a subsequent container.

Drug Abuse And Dependence

None known.

Read the entire FDA prescribing information for Copper (Cupric Chloride Injection)


Vitamin D Deficiency: How Much Vitamin D Is Enough? See Slideshow

© Copper Patient Information is supplied by Cerner Multum, Inc. and Copper Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

Health Solutions From Our Sponsors