Coreg vs. Zebeta

Are Coreg and Zebeta the Same Thing?

Coreg (carvedilol) and Zebeta (bisoprolol fumarate) are beta-blockers used to treat high blood pressure (hypertension).

Coreg is also used to treat heart failure and left ventricular dysfunction after a heart attack.

What Are Possible Side Effects of Coreg?

Common side effects of Coreg include:

Contact your doctor if you experience serious side effects of Coreg including

What Are Possible Side Effects of Zebeta?

Common side effects of Zebeta include:

Tell your doctor if you experience unlikely but serious side effects of Zebeta including:

  • very slow heartbeat,
  • severe dizziness,
  • fainting,
  • blue fingers/toes,
  • trouble breathing, or
  • mental/mood changes (such as confusion, mood swings, depression).

What Is Coreg?

Coreg is a prescription medicine that belongs to a group of medicines called "beta-blockers". Coreg is used, often with other medicines, for the following conditions:

  • to treat patients with certain types of heart failure
  • to treat patients who had a heart attack that worsened how well the heart pumps
  • to treat patients with high blood pressure (hypertension)
  • Coreg is not approved for use in children under 18 years of age.

What Is Zebeta?

Zebeta (bisoprolol fumarate) is a type of antihypertensive drug called a beta-adrenergic receptor blocking agent (beta blocker) used to treat hypertension (high blood pressure). Zebeta is available in generic form.


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What Drugs Interact With Coreg?

Coreg may interact with cimetidine, diabetes medications, heart medicines, MAO inhibitors, and medicine to treat psychiatric disorders.

Coreg may also interact with allergy treatments (or if you are undergoing allergy skin-testing), cyclosporine, fluconazole, rifampin, antidepressants, blood pressure medicines, heart rhythm medications, HIV or AIDS medicines, medicine to prevent or treat nausea and vomiting, or narcotics.

What Drugs Interact With Zebeta?

Zebeta may interact with other medications including other beta blockers, heart medicines, clonidine, digitalis, disopyramide, guanethidine, rifampin, insulin or diabetes medication you take by mouth, and medicine for asthma or other breathing disorders.

How Should Coreg Be Taken?

It is important for you to take your medicine every day as directed by your doctor. If you stop taking Coreg suddenly, you could have chest pain and/or a heart attack. If your doctor decides that you should stop taking Coreg, your doctor may slowly lower your dose over a period of time before stopping it completely.

  • Take Coreg exactly as prescribed. Your doctor will tell you how many tablets to take and how often. In order to minimize possible side effects, your doctor might begin with a low dose and then slowly increase the dose.
  • Do not stop taking Coreg and do not change the amount of Coreg you take without talking to your doctor.
  • Tell your doctor if you gain weight or have trouble breathing while taking Coreg.
  • Take Coreg with food.
  • If you miss a dose of Coreg, take your dose as soon as you remember, unless it is time to take your next dose. Take your next dose at the usual time. Do not take 2 doses at the same time.
  • If you take too much Coreg, call your doctor or poison control center right away.

How Should Zebeta Be Taken?

The dose of Zebeta is individualized to the needs of the patient, ranging from 2.5 to 20 mg once daily.


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GSK. Coreg Product Information.
FDA. Zebeta Product Information.

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