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Cortisporin Ophthalmic Ointment

Last reviewed on RxList: 6/21/2017
Cortisporin Ophthalmic Ointment Side Effects Center

Last reviewed on RxList 6/21/2017

Cortisporin Ophthalmic Ointment (neomycin and polymyxin B sulfates, bacitracin zinc, and hydrocortisone) is a combination of antibiotics and a steroid used for steroid- responsive inflammatory ocular (eye) conditions for which a corticosteroid is indicated and where bacterial infection or a risk of bacterial infection exists. The brand name Cortisporin Ophthalmic Ointment is discontinued, but generic versions may be available. Common side effects of Cortisporin Ophthalmic Ointment (neomycin and polymyxin B sulfates, bacitracin zinc, and hydrocortisone) include:

  • eye itching
  • swelling
  • redness
  • irritation, and
  • infection

Apply Cortisporin Ophthalmic Ointment in the affected eye every 3 or 4 hours, depending on the severity of the condition. Cortisporin Ophthalmic Ointment may interact with other drugs. Tell your doctor all medications and supplements you use. During pregnancy, Cortisporin Ophthalmic Ointment should be used only if prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Our Cortisporin Ophthalmic Ointment (neomycin and polymyxin B sulfates, bacitracin zinc, and hydrocortisone) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Cortisporin Ophthalmic Ointment Professional Information


Adverse reactions have occurred with corticosteroid/anti-infective combination drugs which can be attributed to the corticosteroid component, the anti-infective component, or the combination. The exact incidence is not known.

Reactions occurring most often from the presence of the anti-infective ingredient are allergic sensitization reactions including itching, swelling, and conjunctival erythema (see WARNINGS). More serious hypersensitivity reactions, including anaphylaxis, have been reported rarely.

The reactions due to the corticosteroid component in decreasing order of frequency are: elevation of intraocular pressure (IOP) with possible development of glaucoma, and infrequent optic nerve damage; posterior subcapsular cataract formation; and delayed wound healing.

Secondary Infection: The development of the secondary ocular infection has occurred after use of combinations containing corticosteroids and antimicrobials. Fungal and viral infections of the cornea are particularly prone to develop coincidentally with long-term applications of a corticosteroid. The possibility of fungal invasion must be considered in any persistent corneal ulceration where corticosteroid treatment has been used (see WARNINGS).

Local irritation on installation has been reported.

If signs and symptoms fail to improve after two days, the patient should be re-evaluated (see PRECAUTIONS).

Read the entire FDA prescribing information for Cortisporin Ophthalmic Ointment (Neomycin and Polymyxin B Sulfates, Bacitracin Zinc, and Hydrocortisone Ophthalmic )

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© Cortisporin Ophthalmic Ointment Patient Information is supplied by Cerner Multum, Inc. and Cortisporin Ophthalmic Ointment Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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