Cosentyx Side Effects Center

Last updated on RxList: 1/6/2022
Cosentyx Side Effects Center

What Is Cosentyx?

Cosentyx (secukinumab) for Injection is a human interleukin-17A antagonist used to treat moderate to severe plaque psoriasis in adult patients who are candidates for systemic therapy or phototherapy.

What Are Side Effects for Cosentyx?

Common side effects of Cosentyx include:

Dosage for Cosentyx

The recommended dose of Cosentyx is 300 mg by subcutaneous injection at Weeks 0, 1, 2, 3, and 4 followed by 300 mg every 4 weeks. Each 300 mg dose is given as 2 subcutaneous injections of 150 mg.

What Drugs, Substances, or Supplements Interact with Cosentyx?

Cosentyx may interact with:

  • warfarin,
  • cyclosporine, or
  • "live" vaccines.

Tell your doctor all medications and supplements you use and all vaccines you recently received.

Cosentyx During Pregnancy and Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant before using Cosentyx. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Cosentyx (secukinumab) for Injection Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Psoriasis causes the top layer of skin cells to become inflamed and grow too quickly and flake off. See Answer
Cosentyx Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; chest tightness, difficult breathing; feeling like you might pass out; swelling of your face, lips, tongue, or throat.

Call your doctor right away if you have signs of infection such as:

  • redness, warmth, or painful sores on your skin;
  • cough, shortness of breath, cough with red or pink mucus;
  • increased urination, burning when you urinate;
  • sores or white patches in your mouth or throat (yeast infection or "thrush");
  • new or worsening diarrhea or stomach pain; or
  • fever, chills, sweating, muscle pain, weight loss.

Further doses may be delayed until your infection clears up.

Common side effects may include:

  • diarrhea; or
  • cold symptoms such as stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Cosentyx (Secukinumab Injection)


Types of Psoriasis: Medical Pictures and Treatments See Slideshow
Cosentyx Professional Information


The following adverse effects were observed in clinical trials at a frequency of less than 1% of 538 patients: dizziness, fever, flush, headache, hypotension, changes in liver enzymes, joint pain, nausea, sweating, and weakness. These adverse effects were transient. Also in clinical trials, there was one reported case of bradycardia and one case of decreased hematocrit and hemoglobin.

Pentetreotide is derived from octreotide which is used as a therapeutic agent to control symptoms from certain tumors. The usual dose for indium In-111 pentetreotide is approximately 5 to 20 times less than for octreotide and is subtherapeutic. The following adverse reactions have been associated with octreotide in 3% to 10% of patients: nausea, injection site pain, diarrhea, abdominal pain/discomfort, loose stools, and vomiting. Hypertension and hyper- and hypoglycemia have also been reported with the use of octreotide.

The following adverse reactions have been identified during postapproval use of Octreoscan. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Immune System Disorders

Hypersensitivity reactions, predominantly rash, pruritus, less frequently angioedema or features of anaphylaxis.


No Information Provided

Read the entire FDA prescribing information for Cosentyx (Secukinumab Injection)

© Cosentyx Patient Information is supplied by Cerner Multum, Inc. and Cosentyx Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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