Creon 10 Side Effects Center

Last updated on RxList: 2/8/2022
Creon 10 Side Effects Center

What Is Creon 10?

Creon 10 Minimicrospheres (pancrelipase) Delayed-release Capsules is a combination of three enzymes (proteins): lipase, protease, and amylase, and is used to replace these enzymes when the body does not have enough of its own. Certain medical conditions can cause this lack of enzymes, including cystic fibrosis, chronic inflammation of the pancreas, or blockage of the pancreatic ducts. Creon 10 Minimicrospheres may also be used following surgical removal of the pancreas.

What Are Side Effects of Creon 10?

Common side effects of Creon 10 Minimicrospheres include:

  •  diarrhea
  • constipation
  • stomach pain or upset
  • abdominal cramps
  • dizziness
  • nausea
  • vomiting
  • bloating or gas
  • greasy stools
  • rectal irritation
  • headache
  • cough, or
  • weight loss

Dosage for Creon 10

The usual starting dosage for adults and children over age 6 is one to two Creon 10 Capsules per meal or snack. The usual starting dosage for children under 6 years is up to one Creon 10 Capsule per meal or snack.

What Drugs, Substances, or Supplements Interact with Creon 10?

Creon 10 may interact with other drugs. Tell your doctor all medications and supplements you use.

Creon 10 During Pregnancy and Breastfeeding

During pregnancy, Creon 10 should be used only if prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Creon 10 Minimicrospheres (pancrelipase) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Creon 10 Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • joint pain or swelling; or
  • symptoms of a rare but serious bowel disorder--severe or unusual stomach pain, vomiting, bloating, diarrhea, constipation.

Tell your doctor if your child is not growing at a normal rate while using pancrelipase.

Common side effects may include:

  • stomach pain, gas, vomiting;
  • diarrhea, frequent or abnormal bowel movements;
  • rectal itching;
  • headache, dizziness;
  • runny or stuffy nose, cough, sore throat; or
  • changes in your blood sugar.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Creon 10 Professional Information


The most frequently reported adverse reactions to pancreatic enzyme-containing products are gastrointestinal in nature which may include nausea, vomiting, bloating, cramping, constipation or diarrhea. Less frequently, allergic-type reactions have also been observed. Very high doses of pancreatin have been associated with hyperuricosuria and hyperuricemia.

Read the entire FDA prescribing information for Creon 10 (Pancrelipase Delayed-Released Capsules)

© Creon 10 Patient Information is supplied by Cerner Multum, Inc. and Creon 10 Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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