Medical Editor: John P. Cunha, DO, FACOEP
Cyclocort (amcinonide) is a high potency topical corticosteroid indicated for the relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses for a maximum duration of 5 days on the face, axillae, scrotum and scalp and a maximum of 3 weeks on the body. Common side effects of Cyclocort include:
- itchy skin, and
- skin burning or pain at the application site.
Use of Cyclocort for a long period of time, over a large body surface, or use under an airtight dressing, may cause the following rare side effects including:
- weight gain,
- moon face/rounding of the face,
- skin thinning,
- stretch marks,
- skin wrinkling,
- skin dryness,
- the appearance of blood vessels under the surface of your skin,
- skin discoloration,
- skin infection,
- increased body hair,
- hair loss,
- allergic reaction,
- inflammation of hair follicles,
- worsening of condition,
- rash or hives,
- dermatitis (a type of eczema),
- upper abdominal pain,
- prickly heat rash, or
Apply a thin layer dose of Cyclocort to affected area once or twice daily and gently rub in. Allow adequate time for absorption after each application before applying an emollient. Cyclocort may interact with ritonavir and itraconazole, and it may impair the effectiveness of latex products (e.g. condoms, diaphragms). Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Cyclocort; it is unknown if it will harm a fetus. The minimum quantity Cyclocort should be used for the minimum duration in pregnant patients. It is unknown if Cyclocort passes into breast milk. Systemically administered corticosteroids pass into breast milk. Nursing mothers must not apply Cyclocort to the breast area in order to prevent direct contact of the nursing infant with the active ingredient. Consult your doctor before breastfeeding.
Our Cyclocort (amcinonide) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Post-Market Adverse Drug Reactions
The following adverse reactions are reported when topical corticosteroids are used as recommended. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish causal relationship to drug exposure.
Hypothalamic-pituitary adrenal (HPA) axis suppression, cushingoid features (e.g. moon face, central obesity), delayed weight gain/growth retardation in children, osteoporosis, hyperglycemia/glucosuria, hypertension, increased weight/obesity, decreased endogenous cortisol levels, steroid withdrawal syndrome
glaucoma, cataract subcapsular
upper abdominal pain
General Disorders And Administration Site Conditions
Application site irritation/pain.
Immune System Disorders
local hypersensitivity (see Skin And Subcutaneous Tissue Disorders)
Infections And Infestations
Decreased glucose tolerance has also been reported
Skin And Subcutaneous Tissue Disorders
skin striae, skin atrophy, telangiectasia, purpura-like bleeding, acne, dermatitis, hypertrichosis, skin depigmentation, erythema, burning sensation, pruritus, eczema, dryness, itching, local irritation, atrophy of the subcutaneous tissues, pustules, miliaria, folliculitis, pyoderma, allergic contact dermatitis, acneiform eruptions, perioral dermatitis, rash, urticaria, pustular psoriasis, skin wrinkling, alopecia, trichorrhexis, skin infection.
Read the entire FDA prescribing information for Cyclocort (amcinonide)