Cymbalta vs. Pristiq

Are Cymbalta and Pristiq the Same Thing?

Cymbalta (duloxetine) and Pristiq (desvenlafaxine) are selective serotonin and norepinephrine reuptake inhibitor (SNRI) type antidepressants used to treat depression.

Cymbalta is also used to treat anxiety disorder, and pain associated with diabetic peripheral neuropathy or fibromyalgia.

What Are Possible Side Effects of Cymbalta?

Common side effects of Cymbalta include:

What Are Possible Side Effects of Pristiq?

Common side effects of Pristiq include:

What Is Cymbalta?

Cymbalta is a prescription medicine used to treat a certain type of depression called Major Depressive Disorder (MDD). Cymbalta belongs to a class of medicines known as SNRIs (or serotonin-norepinephrine reuptake inhibitors).

Cymbalta is also used to treat or manage:

What Is Pristiq?

Pristiq (desvenlafaxine) is type of antidepressant called a selective serotonin and norepinephrine reuptake inhibitor (SNRI) used to treat major depressive disorder.

SLIDESHOW

Learn to Spot Depression: Symptoms, Warning Signs, Medication See Slideshow

What Drugs Interact With Cymbalta?

Do Not take Cymbalta if you:

  • take a Monoamine Oxidase Inhibitor (MAOI). Ask your healthcare provider or pharmacist if you are not sure if you take an MAOI, including the antibiotic linezolid or intravenous methylene blue.
  • Do not take an MAOI within 5 days of stopping Cymbalta unless directed to do so by your healthcare provider.
  • Do not start Cymbalta if you stopped taking an MAOI in the last 14 days unless directed to do so by your healthcare provider.

Tell your healthcare provider about all the medicines that you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Cymbalta and some medicines may interact with each other, may not work as well, or may cause serious side effects.

Especially tell your healthcare provider if you take:

Ask your healthcare provider for a list of these medicines if you are not sure.

Do not take Cymbalta with any other medicine that contain duloxetine.

What Drugs Interact With Pristiq?

Pristiq may interact with cold or allergy medicines, sedatives, narcotics, sleeping pills, muscle relaxers, medicines for seizures or anxiety, other antidepressants, nonsteroidal anti-inflammatory drugs (NSAIDs), blood thinners, St. John's wort, tramadol, L-tryptophan, heart medications, or medicines to treat migraines.

Pristiq may also interact with diuretics (water pills), linezolid, lithium, metoclopramide, midazolam, antibiotics, antifungals, blood pressure medications, or HIV/AIDS medicines.

How Should Cymbalta Be Taken?

Take Cymbalta exactly as your healthcare provider tells you to take it. Your healthcare provider may need to change the dose of Cymbalta until it is the right dose for you.

Swallow Cymbalta whole. Do not chew or crush Cymbalta.

Do not open the capsule and sprinkle on food or mix with liquids. Opening the capsule may affect how well Cymbalta works.

Cymbalta may be taken with or without food.

If you miss a dose of Cymbalta, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of Cymbalta at the same time.

If you take too much Cymbalta, call your healthcare provider or poison control center at 1-800-222-1222 right away, or get emergency treatment.

How Should Pristiq Be Taken?

The recommended dose for Pristiq is 50 mg once daily, with or without food.

QUESTION

Depression is a(n) __________ . See Answer
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References

Lilly. Cymbalta Medication Guide.
https://pi.lilly.com/us/cymbalta-pi.pdf
Pfizer. Pristiq Prescribing Information.
https://www.pristiq.com

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