Are Cymbalta and Pristiq the Same Thing?
What Are Possible Side Effects of Cymbalta?
Common side effects of Cymbalta include:
- dry mouth,
- tired feeling,
- difficulty sleeping,
- loss of appetite, and
What Are Possible Side Effects of Pristiq?
Common side effects of Pristiq include:
- increased or excessive sweating,
- dry mouth,
- sleep problems (insomnia),
- loss of appetite,
- tightness in your jaw,
- weight loss,
- blurred vision,
- decreased sex drive,
- impotence, or
- difficulty having an orgasm.
What Is Cymbalta?
Cymbalta is a prescription medicine used to treat a certain type of depression called Major Depressive Disorder (MDD). Cymbalta belongs to a class of medicines known as SNRIs (or serotonin-norepinephrine reuptake inhibitors).
Cymbalta is also used to treat or manage:
- Generalized Anxiety Disorder (GAD)
- Diabetic Peripheral Neuropathic Pain (DPNP)
- Fibromyalgia (FM)
- Chronic Musculoskeletal Pain
What Is Pristiq?
Pristiq (desvenlafaxine) is type of antidepressant called a selective serotonin and norepinephrine reuptake inhibitor (SNRI) used to treat major depressive disorder.
What Drugs Interact With Cymbalta?
Do Not take Cymbalta if you:
- take a Monoamine Oxidase Inhibitor (MAOI). Ask your healthcare provider or pharmacist if you are not sure if you take an MAOI, including the antibiotic linezolid or intravenous methylene blue.
- Do not take an MAOI within 5 days of stopping Cymbalta unless directed to do so by your healthcare provider.
- Do not start Cymbalta if you stopped taking an MAOI in the last 14 days unless directed to do so by your healthcare provider.
Tell your healthcare provider about all the medicines that you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Cymbalta and some medicines may interact with each other, may not work as well, or may cause serious side effects.
Especially tell your healthcare provider if you take:
- triptans used to treat migraine headache
- medicines used to treat mood, anxiety, psychotic or thought disorders, including tricyclics, lithium, buspirone, SSRIs, SNRIs or MAOIs
- tramadol and fentanyl
- the antibiotics ciprofloxacin, enoxacin
- medicine to treat irregular heart rate (like propafenone, flecainide, quinidine)
- the blood thinner warfarin (Coumadin, Jantoven)
- non-steroidal anti-inflammatory drug (NSAID) (like ibuprofen, naproxen or aspirin).
- over-the-counter supplements such as tryptophan or St. John's Wort
- thioridazine (Mellaril). Mellaril together with Cymbalta can cause serious heart rhythm problems or sudden death.
Ask your healthcare provider for a list of these medicines if you are not sure.
Do not take Cymbalta with any other medicine that contain duloxetine.
What Drugs Interact With Pristiq?
Pristiq may interact with cold or allergy medicines, sedatives, narcotics, sleeping pills, muscle relaxers, medicines for seizures or anxiety, other antidepressants, nonsteroidal anti-inflammatory drugs (NSAIDs), blood thinners, St. John's wort, tramadol, L-tryptophan, heart medications, or medicines to treat migraines.
How Should Cymbalta Be Taken?
Take Cymbalta exactly as your healthcare provider tells you to take it. Your healthcare provider may need to change the dose of Cymbalta until it is the right dose for you.
Swallow Cymbalta whole. Do not chew or crush Cymbalta.
Cymbalta may be taken with or without food.
If you miss a dose of Cymbalta, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of Cymbalta at the same time.
If you take too much Cymbalta, call your healthcare provider or poison control center at 1-800-222-1222 right away, or get emergency treatment.
How Should Pristiq Be Taken?
The recommended dose for Pristiq is 50 mg once daily, with or without food.
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Lilly. Cymbalta Medication Guide.
Pfizer. Pristiq Prescribing Information.