Dantrium Capsules

Last reviewed on RxList: 12/15/2020
Dantrium Capsules Side Effects Center

What Is Dantrium?

Dantrium (dantrolene sodium) is a muscle relaxant used to treat muscle spasticity (stiffness and spasms) caused by conditions such as a spinal cord injury, stroke, cerebral palsy, or multiple sclerosis. Dantrium is also used to prevent muscle stiffness and spasms caused by malignant hyperthermia (a rapid rise in body temperature) that can occur during surgery with certain types of anesthesia. Dantrium is available in generic form.

What Are Side Effects of Dantrium?

Common side effects of Dantrium include:

  • drowsiness,
  • dizziness,
  • weakness,
  • tiredness,
  • nausea,
  • vomiting,
  • stomach pain, and
  • diarrhea as the body adjusts to this medication, which usually lessens after several days

Other side effects of Dantrium include headache, constipation, slurred speech, drooling, problems with balance or walking, headache, confusion, vision problems, sleep problems (insomnia), or urinating more than usual.

Dosage for Dantrium

The usual adult dosage schedule for Dantrium is 25 mg once daily for seven days, then 25 mg three times daily for seven days, then 50 mg three times daily for seven days, and up to 100 mg three times daily.

What Drugs, Substances, or Supplements Interact with Dantrium?

Dantrium may interact with cold or allergy medicine, sedatives, narcotics, sleeping pills, medicine for seizures, depression or anxiety, other muscle relaxers, birth control pills and other hormones, or heart or blood pressure medications. Tell your doctor all medications and supplements you use.

Dantrium During Pregnancy and Breastfeeding

During pregnancy, Dantrium should be used only when prescribed. This drug passes into breast milk and could have undesirable effects on a nursing infant. Breastfeeding is not recommended while using this drug.

Additional Information

Our Dantrium (dantrolene sodium) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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Dantrium Capsules Consumer Information

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Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor right away if you have signs of liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes). These side effects may be most likely to occur between 3 and 12 months of your treatment with dantrolene.

Also call your doctor right away if you have:

  • severe drowsiness;
  • severe muscle weakness;
  • weak or shallow breathing;
  • severe or ongoing vomiting or diarrhea;
  • problems with vision or speech;
  • painful or difficult urination;
  • a seizure; or
  • a light-headed feeling, like you might pass out.

Common side effects may include:

  • dizziness, drowsiness;
  • diarrhea;
  • weakness; or
  • feeling tired.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Dantrium Capsules (Dantrolene Sodium Capsules)

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Dantrium Capsules Professional Information

SIDE EFFECTS

The most frequently occurring side effects of Dantrium have been drowsiness, dizziness, weakness, general malaise, fatigue, and diarrhea. These are generally transient, occurring early in treatment, and can often be obviated by beginning with a low dose and increasing dosage gradually until an optimal regimen is established. Diarrhea may be severe and may necessitate temporary withdrawal of Dantrium therapy. If diarrhea recurs upon readministration of Dantrium, therapy should probably be withdrawn permanently.

Other less frequent side effects, listed according to system, are:

Gastrointestinal: Constipation, rarely progressing to signs of intestinal obstruction, GI bleeding, anorexia, swallowing difficulty, gastric irritation, abdominal cramps, nausea and/or vomiting.

Hepatobiliary: Hepatitis (see WARNINGS).

Neurologic: Speech disturbance, seizure, headache, light-headedness, visual disturbance, diplopia, alteration of taste, insomnia, drooling.

Cardiovascular: Tachycardia, erratic blood pressure, phlebitis, heart failure.

Hematologic: Aplastic anemia, anemia, leukopenia, lymphocytic lymphoma, thrombocytopenia.

Psychiatric: Mental depression, mental confusion, increased nervousness.

Urogenital: Increased urinary frequency, crystalluria, hematuria, difficult erection, urinary incontinence and/or nocturia, difficult urination and/or urinary retention.

Integumentary: Abnormal hair growth, acne-like rash, pruritus, urticaria, eczematoid eruption, sweating.

Musculoskeletal: Myalgia, backache.

Respiratory: Feeling of suffocation, respiratory depression.

Special Senses: Excessive tearing.

Hypersensitivity: Pleural effusion with pericarditis, pleural effusion with associated eosinophilia, anaphylaxis.

Other: Chills and fever.

The published literature has included some reports of Dantrium use in patients with Neuroleptic Malignant Syndrome (NMS). Dantrium capsules are not indicated for the treatment of NMS and patients may expire despite treatment with Dantrium capsules.

For medical advice about adverse reactions contact your medical professional. To report SUSPECTED ADVERSE REACTIONS, contact Par Pharmaceutical, at 1-800-828-9393 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Read the entire FDA prescribing information for Dantrium Capsules (Dantrolene Sodium Capsules)

© Dantrium Capsules Patient Information is supplied by Cerner Multum, Inc. and Dantrium Capsules Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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