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Daypro Alta

Last reviewed on RxList: 5/15/2019
Daypro Alta Side Effects Center

Last reviewed on RxList 5/15/2019

Daypro Alta (oxaprozin potassium tablets) is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of inflammation and the pain, fever, swelling and tenderness of joints caused by osteoarthritis and rheumatoid arthritis. Daypro Alta is available in generic form. Common side effects of Daypro Alta include:

  • skin itching or rash,
  • ringing in the ears,
  • headaches,
  • dizziness,
  • nervousness,
  • drowsiness,
  • abdominal or stomach pain,
  • upset stomach,
  • nausea,
  • diarrhea,
  • constipation,
  • bloating,
  • gas,
  • heartburn,
  • fluid retention,
  • shortness of breath,
  • dry mouth,
  • increased sweating,
  • runny nose, or
  • blurred vision.

Tell your doctor if you have serious side effects of Daypro Alta including:

  • chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance;
  • black, bloody, or tarry stools, coughing up blood or vomit that looks like coffee grounds;
  • urinating less than usual or not at all;
  • loss of appetite, dark urine, clay-colored stools, yellowing of the skin or eyes;
  • fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
  • bruising, severe tingling, numbness, pain, or muscle weakness.

The usual dose of Daypro Alta is 600 or 1200 mg once daily taken with food. The maximum dose is 1800 mg daily. Daypro Alta may interact with lithium, blood pressure medications, methotrexate, antibiotics, or blood thinners. Tell your doctor all medications and supplements you use. Daypro Alta should not be taken during pregnancy. It is unknown if Daypro Alta passes into breast milk. Consult your doctor before breastfeeding.

Our Daypro Alta (oxaprozin potassium tablets) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION

What joints are most often affected by osteoarthritis? See Answer
Daypro Alta Consumer Information

Get emergency medical help if you have signs of an allergic reaction (hives, sneezing, runny or stuffy nose, wheezing or difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, feeling short of breath.

Stop using oxaprozin and call your doctor at once if you have:

  • a skin rash, no matter how mild;
  • heart problems--swelling, rapid weight gain, feeling short of breath;
  • signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
  • liver problems--nausea, upper stomach pain, itching, tired feeling, flu-like symptoms, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath; or
  • low red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet.

Common side effects may include:

  • nausea, upset stomach;
  • diarrhea, constipation; or
  • rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Daypro Alta (Oxaprozin)

SLIDESHOW

Slideshow: Exercises for Knee Osteoarthritis and Joint Pain See Slideshow
Daypro Alta Professional Information

SIDE EFFECTS

The following adverse reactions are discussed in greater detail in other sections of the labeling:

  • Cardiovascular Thrombotic Events [see WARNINGS AND PRECAUTIONS]
  • GI Bleeding, Ulceration and Perforation [see WARNINGS AND PRECAUTIONS]
  • Hepatotoxicity [see WARNINGS AND PRECAUTIONS]
  • Hypertension [see WARNINGS AND PRECAUTIONS]
  • Heart Failure and Edema [see WARNINGS AND PRECAUTIONS]
  • Renal Toxicity and Hyperkalemia [see WARNINGS AND PRECAUTIONS]
  • Anaphylactic Reactions [see WARNINGS AND PRECAUTIONS]
  • Serious Skin Reactions [see WARNINGS AND PRECAUTIONS]
  • Hematologic Toxicity [see WARNINGS AND PRECAUTIONS]

Clinical Trials Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.

In patients taking DAYPRO ALTA (oxaprozin potassium tablets), oxaprozin, or other NSAIDs , the following are the most frequently reported adverse experiences occurring in approximately 1% to 10% of patients [see Clinical Studies]:

Gastrointestinal experiences including: abdominal pain, anorexia, constipation, diarrhea, dyspepsia, flatulence, gross gastrointestinal bleeding/perforation, GI ulcers (gastric/duodenal), heartburn, nausea, vomiting.

Non-gastrointestinal experiences including: abnormal renal function, anemia, confusion, depression, disturbance of sleep, dizziness, dysuria or frequency, edema, elevated liver enzymes, headaches, increased bleeding time, pruritus, rashes, sedation, somnolence, tinnitus.

Additional Adverse Experiences Reported In Less Than 1% Of Patients

Body as a whole: anaphylactic reactions, appetite changes, death, fever, infection, sepsis, serum sickness.

Cardiovascular system: arrhythmia, blood pressure changes, congestive heart failure, hypertension, hypotension, myocardial infarction, palpitations, syncope, tachycardia, vasculitis.

Digestive system: alteration in taste, dry mouth, eructation, esophagitis, gastritis, glossitis, hematemesis, hemorrhoidal or rectal bleeding, hepatitis, jaundice, liver failure, pancreatitis, stomatitis.

Hemic and lymphatic system: agranulocytosis, aplastic anemia, ecchymosis, eosinophilia, hemolytic anemia, leukopenia, lymphadenopathy, melena, pancytopenia, purpura, thrombocytopenia.

Metabolic and nutritional: hyperglycemia, weight changes.

Nervous system: anxiety, asthenia, coma, convulsions, dream abnormalities, drowsiness, hallucinations, insomnia, malaise, meningitis, nervousness, paresthesia, tremors, vertigo, weakness.

Respiratory system: asthma, dyspnea, pneumonia, pulmonary infections, respiratory depression, sinusitis, symptoms of upper respiratory tract infection.

Skin and appendages: alopecia. angioedema, increased sweating, photosensitivity, pseudoporphyria, exfoliative dermatitis, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell'ssyndrome), urticaria.

Special senses: blurred vision, conjunctivitis, hearing impairment.

Urogenital system: acute interstitial nephritis, acute renal failure, cystitis, decreased menstrual flow, hematuria, increase in menstrual flow, nephrotic syndrome, oliguria/polyuria, proteinuria, renal insufficiency.

Read the entire FDA prescribing information for Daypro Alta (Oxaprozin)

Related Resources for Daypro Alta

Related Health

© Daypro Alta Patient Information is supplied by Cerner Multum, Inc. and Daypro Alta Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

QUESTION

What joints are most often affected by osteoarthritis? See Answer

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