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Daypro

Last reviewed on RxList: 5/15/2019
Daypro Patient Information Including Side Effects

Brand Names: Daypro

Generic Name: oxaprozin

What is oxaprozin (Daypro)?

Oxaprozin is a nonsteroidal anti-inflammatory drug (NSAID).

Oxaprozin is used to treat pain or inflammation caused by osteoarthritis or rheumatoid arthritis in adults. Oxaprozin is also used to treat rheumatoid arthritis in children who are at least 6 years old.

Oxaprozin may also be used for purposes not listed in this medication guide.

What are the possible side effects of oxaprozin (Daypro)?

Get emergency medical help if you have signs of an allergic reaction (hives, sneezing, runny or stuffy nose, wheezing or difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, feeling short of breath.

Stop using oxaprozin and call your doctor at once if you have:

  • a skin rash, no matter how mild;
  • heart problems--swelling, rapid weight gain, feeling short of breath;
  • signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
  • liver problems--nausea, upper stomach pain, itching, tired feeling, flu-like symptoms, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath; or
  • low red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet.

Common side effects may include:

  • nausea, upset stomach;
  • diarrhea, constipation; or
  • rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about oxaprozin (Daypro)?

Oxaprozin can increase your risk of fatal heart attack or stroke. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Oxaprozin may also cause stomach or intestinal bleeding, which can be fatal.

QUESTION

The term arthritis refers to stiffness in the joints. See Answer
Daypro Patient Information including How Should I Take

What should I discuss with my healthcare provider before taking oxaprozin (Daypro)?

Oxaprozin can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Oxaprozin may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using oxaprozin, especially in older adults.

You should not use oxaprozin if you are allergic to it, or if you have:

  • active bleeding in your stomach or intestines; or
  • a history of asthma attack or severe allergic reaction after taking aspirin or an NSAID.

Tell your doctor if you have ever had:

Taking oxaprozin during the last 3 months of pregnancy may harm the unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Oxaprozin is not approved for use by anyone younger than 6 years old.

How should I take oxaprozin (Daypro)?

Follow all directions on your prescription label and read all medication guides. Your doctor may occasionally change your dose. Use the lowest dose that is effective in treating your condition.

Oxaprozin doses are based on weight (especially in children and teenagers). Your dose needs may change if you gain or lose weight.

If you use this medicine long-term, you may need frequent medical tests.

Store oxaprozin at room temperature, away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

SLIDESHOW

Rheumatoid Arthritis (RA) Symptoms & Treatment See Slideshow
Daypro Patient Information including If I Miss a Dose

What happens if I miss a dose (Daypro)?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose (Daypro)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking oxaprozin (Daypro)?

Avoid alcohol. Heavy drinking can increase your risk of stomach bleeding.

Avoid taking aspirin while you are taking oxaprozin.

Ask a doctor or pharmacist before using other medicines for pain, fever, swelling, or cold/flu symptoms. They may contain ingredients similar to oxaprozin (such as aspirin, ibuprofen, ketoprofen, or naproxen).

Oxaprozin could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

What other drugs will affect oxaprozin (Daypro)?

Ask your doctor before using oxaprozin if you take an antidepressant. Taking certain antidepressants with an NSAID may cause you to bruise or bleed easily.

Tell your doctor about all your other medicines, especially:

This list is not complete. Other drugs may affect oxaprozin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information (Daypro)?

Your pharmacist can provide more information about oxaprozin.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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