Daytrana vs. Quillivant XR

Daytrana (methylphenidate) and Quillivant XR (methylphenidate hydrochloride) are central nervous system stimulants used to treat attention deficit hyperactivity disorder (ADHD).

Side effects of Daytrana and Quillivant XR that are similar include stomach/abdominal pain, loss of appetite, weight loss, trouble sleeping (insomnia), dizziness, nausea, vomiting, and irritability.

Side effects of Daytrana that are different from Quillivant XR include local skin reactions (mild redness, irritation, or bumps on the skin under the patch), headache, lightheadedness, vision problems, nervousness, stuffy nose, sore throat, dry mouth, constipation, blue fingers or toes, cold hands or feet, and (rarely) drowsiness.

Side effects of Quillivant XR that are different from Daytrana include upset stomach, anxiety, quickly changing moods, tics, eye pain, rash, the urge to scratch your skin, increased heart rate, and increased blood pressure.

Daytrana may interact with blood pressure medications, blood thinners, clonidine, seizure medicines, and antidepressants.

Quillivant XR may interact with monoamine oxidase inhibitors (MAOIs).

Withdrawal symptoms may occur if you suddenly stop using Daytrana or Quillivant XR.

Side effects of Daytrana include:

• mild redness,
• irritation, or
• bumps on the skin under the patch.

This will usually improve even if the patch is left on. Other side effects of Daytrana include:

• headache,
• stomach pain,
• loss of appetite,
• weight loss,
• trouble sleeping (insomnia),
• dizziness,
• nausea,
• vomiting,
• lightheadedness,
• vision problems,
• irritability,
• nervousness,
• stuffy nose,
• sore throat,
• dry mouth,
• constipation,
• blue fingers or toes,
• cold hands or feet, or
• (rarely) drowsiness.

Daytrana may raise your blood pressure. Check your blood pressure regularly and tell your doctor if the results are high. Tell your doctor if you have serious side effects of Daytrana including:

• numbness/pain/skin color change/sensitivity to temperature in the fingers or toes,
• fast/pounding/irregular heartbeat,
• mental/mood/behavior changes (such as agitation, aggression, mood swings, abnormal thoughts, thoughts of suicide),
• uncontrolled muscle movements (such as twitching, shaking),
• sudden outbursts of words or sounds that are hard to control, or
• slow healing sores or ulcers on the tips of fingers or toes.

Side effects of Quillivant XR include:

• decreased appetite,
• insomnia,
• nausea,
• vomiting,
• upset stomach,
• abdominal pain,
• weight loss,
• anxiety,
• dizziness,
• irritability,
• quickly changing moods,
• tics,
• eye pain,
• rash,
• the urge to scratch your skin,
• increased heart rate, and
• increased blood pressure.

Daytrana (methylphenidate) is a central nervous system stimulant used to treat attention deficit hyperactivity disorder (ADHD).

Quillivant XR (methylphenidate hydrochloride) is a central nervous system (CNS) stimulant used to treat Attention Deficit Hyperactivity Disorder (ADHD). Quillivant XR is available in generic form.

Daytrana may interact with:

• blood pressure medications,
• blood thinners,
• clonidine,
• seizure medicines, or
• antidepressants

Tell your doctor all medications you use.

Quillivant XR may interact with monoamine oxidase inhibitors (MAOIs). Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Quillivant XR; it is unknown if it will affect a fetus. Premature delivery and low birth weight have been seen in mothers dependent on stimulant products such as amphetamines. Quillivant XR passes into breast milk. Breastfeeding while using Quillivant XR is not recommended. Withdrawal symptoms may occur if you suddenly stop taking Quillivant XR.

Daytrana patch should be applied to the hip area 2 hours before an effect is needed and should be removed 9 hours after application. Dose titration, final dosage, and wear time is individualized to the needs and response of the patient.

For patients 6 years of age and above, the recommended starting dose of Quillivant XR is 20 mg given orally once daily in the morning with or without food. The dosage may be increased weekly in increments of 10 mg to 20 mg per day. A daily dosage above 60 mg is not recommended.