Dayvigo vs. Ambien

Reviewed on 10/7/2021

Are Dayvigo and Ambien the Same Thing?

What Are Possible Side Effects of Dayvigo?

Common side effects of Dayvigo include:

  • Drowsiness,
  • Headache, and
  • Nightmares or abnormal dreams

What Are Possible Side Effects of Ambien?

Common side effects of Ambien include:

  • Daytime drowsiness,
  • Dizziness,
  • Weakness,
  • Lightheadedness,
  • "Drugged" feeling,
  • Tiredness,
  • Loss of coordination,
  • Stuffy nose,
  • Nasal irritation,
  • Dry mouth,
  • Sore throat,
  • Nausea,
  • Constipation,
  • Diarrhea,
  • Stomach upset,
  • Headache,
  • Muscle pain,
  • Confusion,
  • Insomnia,
  • Euphoria,
  • Ataxia (balance problems), and
  • Visual changes.

Tell your doctor if you have unlikely but serious side effects of Ambien including:

  • memory loss,
  • mental/mood/behavior changes (such as new or worsening depression, abnormal thoughts, thoughts of suicide, hallucinations, confusion, agitation, aggressive behavior, or anxiety).


What is insomnia? See Answer

What Is Dayvigo?

Dayvigo (lemborexant) is an orexin receptor antagonist used to treat adult patients with insomnia, characterized by difficulties with sleep onset and/or sleep maintenance.

What Is Ambien?

Ambien (zolpidem) is a sedative/hypnotic used for treating insomnia.

What Drugs Interact With Dayvigo?

Dayvigo may interact with other medicines such as:

  • itraconazole,
  • clarithromycin,
  • fluconazole,
  • verapamil,
  • rifampin,
  • carbamazepine,
  • St. John’s wort,
  • bosentan,
  • efavirenz,
  • etravirine,
  • modafinil,
  • alcohol,
  • bupropion, and
  • methadone

Tell your doctor all medications and supplements you use.

What Drugs Interact With Ambien?

  • Ambien may interact with other medicines that make you sleepy or slow your breathing (such as cold medicines, pain medications, muscle relaxants, and medicines for depression, anxiety, or seizures) or antidepressants.
  • Ambien may also interact with alcohol, chlorpromazine, itraconazole, ketoconazole, or rifampin.
  • Insomnia symptoms may also return after you stop taking Ambien.
    • These symptoms may seem to be worse than before you started taking Ambien.

How Should Dayvigo be Taken?

  • The recommended dose of Dayvigo is 5 mg taken no more than once per night, immediately before going to bed, with at least 7 hours remaining before the planned time of awakening.
  • The dosage of Dayvigo may be increased to 10 mg based on clinical response and tolerability.

How Should Ambien be Taken?

The recommended adult dose of Ambien is

  • 10 mg as conventional tablets or spray or
  • 12.5 mg as extended-release tablets.


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Eisai Inc. Dayvigo Drug Information.

Sanofi-Aventis. Ambien Product Information

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