Dayvigo vs. Sonata

Reviewed on 10/7/2021

Are Dayvigo and Sonata the Same Thing?

What Are Possible Side Effects of Dayvigo?

Common side effects of Dayvigo include:

  • drowsiness,
  • headache, and
  • nightmares or abnormal dreams

What Are Possible Side Effects of Sonata?

Common side effects of Sonata include:

  • dizziness,
  • drowsiness,
  • short-term memory loss,
  • problems with memory or concentration,
  • lack of coordination (especially during the first 2 hours after you take the medication),
  • "hangover" feeling,
  • numbness or tingling,
  • anxiety,
  • depression,
  • nervous feeling,
  • problems with vision,
  • headache,
  • nausea,
  • stomach pain,
  • loss of appetite,
  • constipation,
  • dry mouth,
  • increased menstrual pain (cramps),
  • back pain,
  • joint or muscle pain, or
  • mild skin rash.

Taking Sonata properly just before falling asleep will reduce your risk of these effects. Some people using Sonata have engaged in activities such as driving, eating, or making phone calls and later having no memory of the activity. If this happens to you, stop taking Sonata and talk with your doctor about another treatment for your sleep disorder. Tell your doctor if you have unlikely but serious side effects of Sonata including:

  • mental/mood changes (e.g., agitation, confusion, seeing or hearing things that are not there, rare thoughts of suicide), or
  • unusual behavior.


Sleep Disorders: Foods That Help Sleep or Keep You Awake See Slideshow

What Is Dayvigo?

Dayvigo (lemborexant) is an orexin receptor antagonist used to treat adult patients with insomnia, characterized by difficulties with sleep onset and/or sleep maintenance.

What Is Sonata?

Sonata (zaleplon) is a non-benzodiazepine sedative-hypnotic drug used to treat insomnia.

What Drugs Interact With Dayvigo?

Dayvigo may interact with other medicines such as:

  • itraconazole,
  • clarithromycin,
  • fluconazole,
  • verapamil,
  • rifampin,
  • carbamazepine,
  • St. John’s wort,
  • bosentan,
  • efavirenz,
  • etravirine,
  • modafinil,
  • alcohol,
  • bupropion, and
  • methadone

Tell your doctor about all medications and supplements you use.

What Drugs Interact With Sonata?

Sonata may interact with cimetidine, thioridazine, promethazine, cyclosporine, rifampin, antibiotics, antidepressants, narcotic pain medications, muscle relaxers, seizure medications, or anti-anxiety medications.

How Should Dayvigo be Taken?

  • The recommended dose of Dayvigo is 5 mg taken no more than once per night, immediately before going to bed, with at least 7 hours remaining before the planned time of awakening.
  • The dosage of Dayvigo may be increased to 10 mg based on clinical response and tolerability.

How Should Sonata be Taken?

The dose of Sonata should be individualized.

  • The recommended dose for most adults is 10 mg.
  • For some patients, 5 mg may be a sufficient dose.


What is insomnia? See Answer

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Eisai Inc. Dayvigo Drug Information.

Pfizer. Sonata Product Information.

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