DDAVP Injection

Last updated on RxList: 6/27/2017
DDAVP Injection Side Effects Center

Last reviewed on RxList 6/27/2017

DDAVP Injection (desmopressin acetate) is a man-made form of a hormone that occurs naturally in the pituitary gland used to treat hemophilia A or von Willebrand's disease Type I, and is also used to treat central cranial diabetes insipidus, and increased thirst and urination caused by head surgery or head trauma. DDAVP Injection is available in generic form. Common side effects of DDAVP Injection include:

  • headache,
  • nausea,
  • upset stomach,
  • stomach pain,
  • diarrhea,
  • flushing of the face (warmth, redness, or tingly feeling), or
  • injection site reactions (redness, pain, or swelling).

DDAVP Injection can infrequently cause a low level of sodium in the blood, which can be serious and possibly life-threatening. Seek immediate medical attention if you have unlikely but serious symptoms of a low level of sodium in the blood such as:

The dose of DDAVP Injection to treat hemophilia A and von Willebrand's Disease Type I is 4 mcg/mL administered as an intravenous infusion at a dose of 0.3 mcg DDAVP/kg body weight diluted in saline and infused slowly over 15 to 30 minutes. DDAVP Injection may interact with carbamazepine, chlorpromazine, lamotrigine, oxybutynin, vasopressin, narcotics, antidepressants, medicines to treat erectile dysfunction, drugs to treat high blood pressure or prostate disorder, beta-blockers, or NSAIDs (nonsteroidal anti-inflammatory drugs).Tell your doctor all medications and supplements you use. During pregnancy, DDAVP Injection should be used only when prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Our DDAVP Injection (desmopressin acetate) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

SLIDESHOW

Anemia Symptoms and Signs, Types, Treatment and Causes See Slideshow
DDAVP Injection Consumer Information

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Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • low levels of sodium in the body--headache, confusion, hallucinations, muscle cramps, severe weakness, vomiting, loss of coordination, feeling restless or unsteady;
  • a seizure (convulsions);
  • weak or shallow breathing; or
  • a light-headed feeling, like you might pass out.

Common side effects may include:

  • pain, redness, burning, or swelling where the medicine was injected;
  • flushing (warmth, redness, or tingly feeling);
  • headache; or
  • nausea, stomach pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for DDAVP Injection (Desmopressin Acetate Injection)

QUESTION

What is hemophilia? See Answer
DDAVP Injection Professional Information

SIDE EFFECTS

Infrequently, DDAVP has produced transient headache, nausea, mild abdominal cramps and vulval pain. These symptoms disappeared with reduction in dosage. Occasionally, injection of DDAVP has produced local erythema, swelling or burning pain. Occasional facial flushing has been reported with the administration of DDAVP. DDAVP Injection (desmopressin acetate injection) has infrequently produced changes in blood pressure causing either a slight elevation or a transient fall and a compensatory increase in heart rate. Severe allergic reactions including anaphylaxis have been reported rarely with DDAVP Injection.

See WARNINGS for the possibility of water intoxication and hyponatremia.

Post Marketing: There have been rare reports of thrombotic events (acute cerebrovascular thrombosis, acute myocardial infarction) following DDAVP Injection in patients predisposed to thrombus formation, and rare reports of hyponatremic convulsions associated with concomitant use with the following medications: oxybutinin and imipramine.

Read the entire FDA prescribing information for DDAVP Injection (Desmopressin Acetate Injection)

© DDAVP Injection Patient Information is supplied by Cerner Multum, Inc. and DDAVP Injection Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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