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DDAVP Rhinal Tube

Last reviewed on RxList: 6/27/2017
DDAVP Rhinal Tube Side Effects Center

Last reviewed on RxList 6/27/2017

DDAVP Rhinal Tube (desmopressin acetate) is a man-made form of a hormone that occurs naturally in the pituitary gland and is used to treat central cranial diabetes insipidus, and increased thirst and urination caused by head surgery or head trauma. DDAVP Rhinal Tube is also used to treat hemophilia A or von Willebrand's disease Type I. Common side effects of DDAVP Rhinal Tube include:

  • runny or stuffy nose
  • sore throat
  • cough
  • other cold symptoms
  • eye redness or watering
  • eye swelling
  • eye itching
  • increased sensitivity to light
  • nosebleed
  • headache
  • weakness
  • dizziness
  • agitation
  • nausea
  • vomiting
  • stomach or abdominal pain
  • hot or cold feeling
  • chills, or
  • flushing (warmth, redness, or tingly feeling in your face)

DDAVP Rhinal Tube dosage is determined for each individual patient and adjusted according to the pattern of response. DDAVP Rhinal Tube may interact with carbamazepine, chlorpromazine, lamotrigine, oxybutynin, vasopressin, narcotics, antidepressants, medicine to treat erectile dysfunction, drugs to treat high blood pressure or a prostate disorder, beta-blockers, or NSAIDs (nonsteroidal anti-inflammatory drugs). Tell your doctor all medications and supplements you use. DDAVP Rhinal Tube is not expected to harm a fetus. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is unknown if DDAVP Rhinal Tube nasal passes into breast milk, or if it could harm a nursing baby. Consult your doctor before breastfeeding.

Our DDAVP Rhinal Tube (desmopressin acetate) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

DDAVP Rhinal Tube Consumer Information

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using desmopressin nasal and call your doctor at once if you have any of these serious side effects:

  • nausea, vomiting, weakness, loss of appetite, headache, feeling restless or irritable, confusion, hallucinations, muscle pain or weakness, and/or seizure;
  • feeling like you might pass out;
  • swelling;
  • chest pain, fast or pounding heart rate;
  • vaginal pain;
  • nosebleed; or
  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

Less serious side effects may include:

  • runny or stuffy nose;
  • sore throat, cough, or other cold symptoms;
  • eye redness or watering;
  • eye itching or increased sensitivity to light;
  • headache, weakness;
  • feeling dizzy or agitated;
  • nausea, vomiting, stomach pain;
  • hot or cold feeling; or
  • warmth, redness, or tingly feeling in your face.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for DDAVP Rhinal Tube (Desmopressin Acetate Rhinal Tube)

DDAVP Rhinal Tube Professional Information


Infrequently, high dosages of intranasal DDAVP have produced transient headache and nausea. Nasal congestion, rhinitis and flushing have also been reported occasionally along with mild abdominal cramps. These symptoms disappeared with reduction in dosage. Nosebleed, sore throat, cough and upper respiratory infections have also been reported.

The following table lists the percent of patients having adverse experiences without regard to relationship to study drug from the pooled pivotal study data for nocturnal enuresis.

DDAVP 20 mcg
DDAVP 40 mcg
  % % %
  Abdominal Pain 0 2 2
  Asthenia 0 0 2
  Chills 0 0 2
  Headache 0 2 5
  Dizziness 0 0 3
  Epistaxis 2 3 0
  Nostril Pain 0 2 0
  Rhinitis 2 8 3
  Gastrointestinal Disorder 0 2 0
  Nausea 0 0 2
  Conjunctivitis 0 2 0
  Edema Eyes 0 2 0
  Lachrymation Disorder 0 0 2

Post Marketing: There have been rare reports of hyponatremic convulsions associated with concomitant use with the following medications: oxybutinin and imipramine.

See WARNINGS for the possibility of water intoxication and hyponatremia.

Read the entire FDA prescribing information for DDAVP Rhinal Tube (Desmopressin Acetate Rhinal Tube)

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© DDAVP Rhinal Tube Patient Information is supplied by Cerner Multum, Inc. and DDAVP Rhinal Tube Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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