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Last reviewed on RxList: 7/5/2019
Deplin Side Effects Center

Last reviewed on RxList 2/1/2018

Deplin (L-methylfolate [from Metafolin] and Algae-S powder [Schizochytrium]) is a prescription medical food for use only under the supervision of a physician for the clinical dietary management of depression and schizophrenia and is specially formulated to meet the distinctive nutritional requirement for these conditions. Common side effects of Deplin include:

  • allergic reactions

The usual adult dose is one Deplin 15 capsule or one or two Deplin 7.5 capsule(s), given daily with or without food or as directed under medical supervision. Deplin may interact with other drugs. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Deplin. Consult your doctor before breastfeeding.

Our Deplin (L-methylfolate [from Metafolin] and Algae-S powder [Schizochytrium]) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Schizophrenia is the most disabling mental illness. See Answer
Deplin Professional Information


Allergic reactions have been reported following the use of oral L-methylfolate.11

Read the entire FDA prescribing information for Deplin (L-methylfolate [from Metafolin] and Algae-S powder [Schizochytrium] Prescription Medical Food)


Schizophrenia: Symptoms, Types, Causes, Treatment See Slideshow
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© Deplin Patient Information is supplied by Cerner Multum, Inc. and Deplin Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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