Desoximetasone Generic Side Effects Center

Last updated on RxList: 2/15/2022
Desoximetasone Generic Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is Desoximetasone Generic?

Desoximetasone Ointment, 0.25% contains the active synthetic corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Desoximetasone ointment is available in generic form.

What Are Side Effects of Desoximetasone Generic?

Common side effects of desoximetasone ointment include:

  • burning,
  • itching,
  • irritation,
  • dryness,
  • hair bumps,
  • excess hair growth,
  • acne,
  • skin discoloration,
  • inflammation and rash around the mouth,
  • allergic contact dermatitis,
  • breakdown of skin,
  • secondary infection,
  • thinning skin,
  • stretch marks, and
  • rash.

Dosage for Desoximetasone Generic

Apply a thin film dose of desoximetasone ointment to the affected skin areas twice daily. Rub in gently.

What Drugs, Substances, or Supplements Interact with Desoximetasone Generic?

Desoximetasone Ointment may interact with other drugs. Tell your doctor all medications and supplements you use.

Desoximetasone Generic During Pregnancy or Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant before using desoximetasone ointment; it is unknown how it will affect a fetus. It is unknown if desoximetasone ointment passes into breast milk. Systemically administered corticosteroids pass into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Desoximetasone Ointment, 0.25% Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Desoximetasone Generic Consumer Information

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Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • worsening of your skin condition;
  • redness, warmth, swelling, oozing, or severe irritation of any treated skin;
  • blurred vision, tunnel vision, eye pain, or seeing halos around lights;
  • high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; or
  • possible signs of absorbing this medicine through your skin--weight gain (especially in your face or your upper back and torso), slow wound healing, thinning or discolored skin, increased body hair, muscle weakness, nausea, diarrhea, tiredness, mood changes, menstrual changes, sexual changes.

Common side effects may include:

  • rash, itching, or irritation around your mouth;
  • burning, irritation, itching, or dryness of treated skin;
  • redness or crusting around your hair follicles;
  • increased hair growth;
  • blisters, pimples, or crusting of treated skin;
  • changes in color of treated skin;
  • white or "pruned" appearance of the skin; or
  • stretch marks.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Desoximetasone Generic Professional Information


The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence:

Burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, and miliaria.

In controlled clinical studies the incidence of adverse reactions was low (0.3%) for Desoximetasone Ointment and included mild burning sensation at the site of application.

To report SUSPECTED ADVERSE REACTIONS, contact G&W Laboratories , Inc. at 1-800- 922-1038 or FDA at 1-800-FDA-1088 or

Read the entire FDA prescribing information for Desoximetasone Generic (Desoximetasone)

© Desoximetasone Generic Patient Information is supplied by Cerner Multum, Inc. and Desoximetasone Generic Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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