Desoxyn Side Effects Center

Last updated on RxList: 9/30/2020
Desoxyn Side Effects Center

What Is Desoxyn?

Desoxyn (methamphetamine) is a central nervous system stimulant that is used to treat attention deficit hyperactivity disorder (ADHD). Desoxyn is also used to treat obesity after other diets or medications have been tried without successful weight loss.

What Are Side Effects of Desoxyn?

Side effects of Desoxyn include:

  • headache,
  • dizziness,
  • sleep problems (insomnia),
  • dry mouth,
  • unpleasant taste in your mouth,
  • diarrhea,
  • constipation,
  • loss of appetite,
  • weight loss,
  • loss of interest in sex,
  • impotence, or
  • difficulty having an orgasm.

Dosage for Desoxyn?

For treatment of children 6 years or older with a behavioral syndrome characterized by moderate to severe distractibility, short attention span, hyperactivity, emotional lability and impulsivity, an initial dose of 5 mg Desoxyn once or twice a day is recommended. To treat obesity in adults, one 5 mg tablet of Desoxyn should be taken one-half hour before each meal.

What Drugs, Substances, or Supplements Interact with Desoxyn?

Desoxyn may interact with insulin, cold medicines (decongestants), phenothiazines, or antidepressants.

Desoxyn During Pregnancy and Breastfeeding

Tell your doctor all medications and supplements you use. Metamphetamine may be harmful to an unborn baby. It could also cause premature birth, low birth weight, or withdrawal symptoms in a newborn if the mother takes methamphetamine during pregnancy. Methamphetamine can pass into breast milk and may harm a nursing baby. Consult your doctor before breastfeeding. Methamphetamine is a drug of abuse and can be habit-forming.

Additional Information

Our Desoxyn Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


ADHD Symptoms in Children See Slideshow
Desoxyn Consumer Information

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Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • signs of heart problems--chest pain, trouble breathing, feeling like you might pass out;
  • signs of psychosis--hallucinations (seeing or hearing things that are not real), new behavior problems, aggression, hostility, paranoia;
  • signs of circulation problems--numbness, pain, cold feeling, unexplained wounds, or skin color changes (pale, red, or blue appearance) in your fingers or toes;
  • a seizure (convulsions);
  • muscle twitches (tics); or
  • changes in your vision.

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Methamphetamine can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.

Common side effects may include:

  • headache or dizziness;
  • fast heartbeats;
  • sleep problems (insomnia);
  • diarrhea, constipation, upset stomach;
  • tremors; or
  • loss of appetite, weight loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Desoxyn (Methamphetamine Hydrochloride)


The abbreviated term ADHD denotes the condition commonly known as: See Answer
Desoxyn Professional Information


The following are adverse reactions in decreasing order of severity within each category that have been reported:


Elevation of blood pressure, tachycardia and palpitation. Fatal cardiorespiratory arrest has been reported, mostly in the context of abuse/misuse.

Central Nervous System

Psychotic episodes have been rarely reported at recommended doses. Dizziness, dysphoria, overstimulation, euphoria, insomnia, tremor, restlessness and headache. Exacerbation of motor and phonic tics and Tourette’s syndrome.


Diarrhea, constipation, dryness of mouth, unpleasant taste and other gastrointestinal disturbances.




Impotence and changes in libido; frequent or prolonged erections.




Suppression of growth has been reported with the long-term use of stimulants in children (see WARNINGS).

To report SUSPECTED ADVERSE REACTIONS, contact Recordati Rare Diseases Inc. at 1-888-575-8344 or FDA at 1-800-FDA-1088 or

Read the entire FDA prescribing information for Desoxyn (Methamphetamine Hydrochloride)

© Desoxyn Patient Information is supplied by Cerner Multum, Inc. and Desoxyn Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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