Dextenza

Last updated on RxList: 4/19/2021
Dextenza Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is Dextenza?

Dextenza (dexamethasone ophthalmic insert) is a corticosteroid indicated for the treatment of ocular pain following ophthalmic surgery.

What Are Side Effects of Dextenza?

Common side effects of Dextenza include:

  • eye inflammation and increased pressure in the eye

Dosage for Dextenza

A single Dextenza ophthalmic insert releases a 0.4 mg dose of dexamethasone for up to 30 days following insertion.

What Drugs, Substances, or Supplements Interact with Dextenza?

Dextenza may interact with other drugs. Tell your doctor all medications and supplements you use.

Dextenza During Pregnancy and Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant before using Dextenza; it is unknown how it would affect a fetus. It is unknown if Dextenza passes into breast milk. Systemically administered corticosteroids pass into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Dextenza (dexamethasone ophthalmic insert) 0.4 Mg, for Intracanalicular Use Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

SLIDESHOW

Pink Eye (Conjunctivitis) Symptoms, Causes, Treatments See Slideshow
Dextenza Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • eye pain or redness;
  • blurred vision, tunnel vision, or seeing halos around lights;
  • cloudy or hazy vision;
  • eyebrow pain;
  • changes in the shape of your pupil;
  • increased sensitivity of your eyes to light; or
  • signs of eye infection--swelling, redness, severe discomfort, crusting or drainage.

Repeat treatments with Ozurdex may cause you to develop cataracts, which can affect your vision and may require surgical treatment. Your doctor will determine how often to treat you with this medicine.

Common side effects may include:

  • vision problems;
  • seeing "floaters" in your vision;
  • eye pain or redness;
  • feeling like something is in your eye;
  • eyelid swelling;
  • dry eyes;
  • headache; or
  • your eyes may be more sensitive to light.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Dextenza (Dexamethasone Ophthalmic Insert)

QUESTION

What causes dry eyes? See Answer
Dextenza Professional Information

SIDE EFFECTS

The following serious adverse reactions are described elsewhere in the labeling:

  • Intraocular Pressure Increase [see WARNINGS AND PRECAUTIONS]
  • Bacterial Infection [see WARNINGS AND PRECAUTIONS]
  • Viral Infection [see WARNINGS AND PRECAUTIONS]
  • Fungal Infection [see WARNINGS AND PRECAUTIONS]
  • Delayed Healing [see WARNINGS AND PRECAUTIONS]

Clinical Trials Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. Adverse reactions associated with ophthalmic steroids include elevated intraocular pressure, which may be associated with optic nerve damage, visual acuity and field defects, posterior subcapsular cataract formation; delayed wound healing; secondary ocular infection from pathogens including herpes simplex, and perforation of the globe where there is thinning of the cornea or sclera [see WARNINGS AND PRECAUTIONS].

DEXTENZA was studied in four randomized, vehicle-controlled studies (n = 567). The mean age of the population was 68 years (range 35 to 87 years), 59% were female, and 83% were white. Forty-seven percent had brown iris color and 30% had blue iris color. The most common ocular adverse reactions that occurred in patients treated with DEXTENZA were: anterior chamber inflammation including iritis and iridocyclitis (10%); intraocular pressure increased (6%); visual acuity reduced (2%); cystoid macular edema (1%); corneal edema (1%); eye pain (1%) and conjunctival hyperemia (1%).

The most common non-ocular adverse reaction that occurred in patients treated with DEXTENZA was headache (1%).

DRUG INTERACTIONS

No Information Provided

Read the entire FDA prescribing information for Dextenza (Dexamethasone Ophthalmic Insert)

© Dextenza Patient Information is supplied by Cerner Multum, Inc. and Dextenza Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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