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Diacomit

Last reviewed on RxList: 9/4/2018

DIACOMIT
(stiripentol) Capsules, for Oral Use

DIACOMIT
(stiripentol) Powder, for Oral Suspension

DESCRIPTION

Table 3. Description

Proprietary Name DIACOMIT
Established Name Stiripentol
Route of Administration Oral
Chemical Name 4,4-dimethyl-l -[3,4-(methylendioxyphenyl)-1 -pentene-3 -ol
Structural Formula DIACOMIT (stiripentol) Structural Formula - Illustration

Stiripentol is a white to pale yellow crystalline powder with a bitter taste; it is practically insoluble in water (at 25°C), sparingly soluble in chloroform, and soluble in acetone, ethanol, ether, acetonitrile, and dichloromethane. The melting point is approximately 75°C. The pKa is 14.2, and measurement of the partition coefficient (water-octanol) provides a Log P value of 2.94. The molecular formula is C14H18O3 and the molecular weight is 234.3.

Capsules

DIACOMIT capsules contain 250 mg (size 2: pink) or 500 mg (size 0: white) of stiripentol. Capsules also contain the following inactive ingredients: erythrosine (250 mg capsule only), gelatin, indigotine (250 mg capsule only), magnesium stearate, povidone, sodium starch glycolate, titanium dioxide.

Powder For Suspension

DIACOMIT powder for oral suspension packets contain 250 mg or 500 mg of stiripentol. DIACOMIT packets also contain the following inactive ingredients: aspartame, carmellose sodium, erythrosine, glucose, hydroxyethylcellulose, povidone, sodium starch glycolate, sorbitol, titanium dioxide, fruit flavor (acacia, Bergamot oil, hypromellose, maltodextrin, sorbitol, and vanillin).

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