How Do Diagnostic Antimicrobials Work?

Reviewed on 9/29/2021

HOW DO DIAGNOSTIC ANTIMICROBIALS WORK?

Tuberculin purified protein derivative (PPD) or Mantoux test belongs to the class of diagnostic antimicrobials and is used to identify tuberculosis infection. It helps to minimize the risk of transmission of infection by early detection and treatment.

PPD is a cell-free purified protein fraction obtained from a human strain of Mycobacterium tuberculosis. When the mycobacterium invades the body, the immune system sends antibodies to attack these microbes. After three to eight weeks, these antibodies enter the bloodstream and then circulate for years. When tuberculin PPD is given, these antibodies react to the purified protein fraction and cause a local reaction.

HOW ARE DIAGNOSTIC ANTIMICROBIALS USED?

Diagnostic antimicrobials are used to identify tuberculosis infection in people who are at an increased risk of developing active disease.

WHAT ARE SIDE EFFECTS OF DIAGNOSTIC ANTIMICROBIALS?

Some of the side effects of diagnostic antimicrobials include:

The information contained herein is not intended to cover all possible side effects, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Check with your doctor or pharmacist to make sure these drugs do not cause any harm when you take them along with other medicines. Never stop taking your medication and never change your dose or frequency without consulting your doctor.

WHAT ARE NAMES OF DIAGNOSTIC ANTIMICROBIALS?

Generic and brand names of diagnostic antimicrobials include:

  • Aplisol
  • Mantoux
  • PPD
  • Sclavo PPD solution
  • Tuberculin purified protein derivative
  • Tubersol

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References
https://reference.medscape.com/drugs/diagnostics-antimicrobials

https://www.fda.gov/media/74866/download

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