Diamox vs. Mannitol

Are Diamox and Mannitol the Same Thing?

Diamox Sequels (acetazolamide) and Mannitol (mannitol injection) are used to treat glaucoma.

Diamox Sequels is also used to treat and to prevent acute mountain sickness (altitude sickness). Diamox Sequels is also used as a part of some treatment plans for congestive heart failure and seizure disorders.

Mannitol is also used to increase urine production, and to treat or prevent medical conditions that are caused by an increase in body fluids/water (e.g., cerebral edema, kidney failure).

What Are Possible Side Effects of Diamox?

Common side effects of Diamox include:

Other side effects of Diamox Sequels include:

Tell your doctor if you have unlikely but serious side effects of Diamox Sequels including:

  • increased body hair,
  • hearing loss,
  • unusual tiredness,
  • persistent nausea or vomiting, or
  • severe stomach or abdominal pain.

What Are Possible Side Effects of Mannitol?

Common side effects of Mannitol include:

What Is Diamox?

Diamox Sequels (acetazolamide) is a carbonic anhydrase inhibitor used to treat glaucoma and to treat and to prevent acute mountain sickness (altitude sickness). Diamox Sequels is also used as a part of some treatment plans for congestive heart failure and seizure disorders.

What Is Mannitol?

Mannitol I.V. (mannitol injection) is a diuretic used to increase urine production, and to treat or prevent medical conditions that are caused by an increase in body fluids/water (e.g., cerebral edema, glaucoma, kidney failure).

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What Drugs Interact With Diamox?

Diamox Sequels may interact with cyclosporine, primidone, diflunisal, aspirin and other salicylates, or lithium. Tell your doctor all medications you use. Diamox Sequels should be used during pregnancy only if prescribed. This medication passes into breast milk but is unlikely to harm a nursing infant.

What Drugs Interact With Mannitol?

Mannitol may interact with other drugs. Tell your doctor all medications and supplements you use.

How Should Diamox Be Taken?

To treat glaucoma, the recommended dosage of Diamox Sequels is 1 capsule (500 mg) two times a day. To treat acute mountain sickness, dosage is 500 mg to 1000 mg daily, in divided doses using tablets or extended-release capsules as appropriate.

How Should Mannitol Be Taken?

The usual adult dosage of Mannitol ranges from 50 to 200 g in a 24-hour period, but in most instances an adequate response will be achieved at a dosage of approximately 100 g/24 hours.

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References

DailyMed. Diamox Sequels Product Information.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=74e47451-2bc8-496e-88ad-c10002ee8e22
DailyMed. Mannitol Product Information.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d12cc802-b538-4065-a264-f474ff3b3043

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