Diamox vs. Methazolamide

Are Diamox and Methazolamide the Same Thing?

Diamox Sequels (acetazolamide) and methazolamide are carbonic anhydrase inhibitors used to treat glaucoma.

Diamox Sequels is also used to treat and to prevent acute mountain sickness (altitude sickness). Diamox Sequels is also used as a part of some treatment plans for congestive heart failure and seizure disorders.

What Are Possible Side Effects of Diamox?

Common side effects of Diamox include:

Other side effects of Diamox Sequels include:

Tell your doctor if you have unlikely but serious side effects of Diamox Sequels including:

  • increased body hair,
  • hearing loss,
  • unusual tiredness,
  • persistent nausea or vomiting, or
  • severe stomach or abdominal pain.

What Are Possible Side Effects of Methazolamide?

Common side effects of Methazolamide include:

  • decreased appetite,
  • nausea,
  • vomiting,
  • constipation,
  • diarrhea,
  • changes in taste,
  • drowsiness,
  • dizziness,
  • fatigue,
  • weakness,
  • nervousness,
  • tremor,
  • headache,
  • confusion,
  • increased sensitivity of the skin to sunlight,
  • worsening gout,
  • loss of blood sugar control (if you are diabetic),
  • ringing in your ears (tinnitus) or hearing problems,
  • changes in vision,
  • tingling feeling in the extremities,
  • general feeling of being unwell (malaise), and
  • increased urination.

What Is Diamox?

Diamox Sequels (acetazolamide) is a carbonic anhydrase inhibitor used to treat glaucoma and to treat and to prevent acute mountain sickness (altitude sickness). Diamox Sequels is also used as a part of some treatment plans for congestive heart failure and seizure disorders.

What Is Methazolamide?

Methazolamide is a carbonic anhydrase inhibitor used to treat glaucoma. Methazolamide is available in generic form.

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What Drugs Interact With Diamox?

Diamox Sequels may interact with cyclosporine, primidone, diflunisal, aspirin and other salicylates, or lithium. Tell your doctor all medications you use. Diamox Sequels should be used during pregnancy only if prescribed. This medication passes into breast milk but is unlikely to harm a nursing infant.

What Drugs Interact With Methazolamide?

Methazolamide may interact with cyclosporine, primidone, diflunisal, aspirin or other salicylates, or lithium. Tell your doctor all medications and supplements you use. During pregnancy, methazolamide should be taken only if prescribed.

How Should Diamox Be Taken?

To treat glaucoma, the recommended dosage of Diamox Sequels is 1 capsule (500 mg) two times a day. To treat acute mountain sickness, dosage is 500 mg to 1000 mg daily, in divided doses using tablets or extended-release capsules as appropriate.

How Should Methazolamide Be Taken?

The effective therapeutic dose of methazolamide varies from 50mg to 100mg, 2 or 3 times daily. The drug may be used at the same time as miotic and osmotic agents.

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References

DailyMed. Diamox Sequels Product Information.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=74e47451-2bc8-496e-88ad-c10002ee8e22
DailyMed. Methazolamide Product Information.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b452d353-8094-4da3-8751-7cd3e88b8322

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