Diflucan vs. Nystatin

Are Diflucan and Nystatin the Same Thing?

Diflucan (fluconazole) and nystatin are antifungal medications used to treat Candida fungal infections.

Diflucan is also used to treat fungal meningitis and may be prescribed to ward off fungal infections in patients being treated with chemotherapy or radiation before a bone marrow transplant.

Nystatin comes in several forms. Oral nystatin is used to treat oral thrush, and the cream or powder forms of nystatin are used topically to treat fungal skin infections.

Brand names for nystatin include Nystatin, Nyamyc, Nystop, and Nyata.

What Are Possible Side Effects of Diflucan?

Common side effects of Diflucan include:

What Are Possible Side Effects of Nystatin?

Common side effects of Nystatin include:

  • skin irritation or redness,
  • nausea,
  • stomach upset,
  • vomiting, or
  • diarrhea

What is Diflucan?

Diflucan (fluconazole) is an antifungal medication prescribed to treat Candida fungal infections of the mouth, vagina, esophagus, lungs, urinary tract, abdomen, and other organs. Diflucan is also used to treat fungal meningitis and may be prescribed to ward off fungal infections in patients being treated with chemotherapy or radiation before a bone marrow transplant.

What is Nystatin?

Nystatin is a topical (for the skin) antifungal used to treat fungal skin infections. Nystatin is available in generic form.

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What Drugs Interact With Diflucan?

Diflucan may interact with blood thinners or seizure medications.

Diflucan may also interact with alfentanil, fentanyl, clopidogrel, cyclophosphamide, cyclosporine, methadone, pimozide, prednisone, saquinavir, zidovudine, sirolimus, tacrolimus, theophylline, voriconazole, antidepressants, cancer medicines, cholesterol lowering medicines, heart or blood pressure medications, nonsteroidal anti-inflammatory drugs (NSAIDs), oral diabetes medications, rifabutin, rifampin, or sedatives.

What Drugs Interact With Nystatin?

There may be other drugs that can interact with Nystatin. Tell your healthcare provider about all your prescription and over-the-counter medications and supplements you use. Do not start a new medication without telling your healthcare provider. Nystatin should be used only if prescribed during pregnancy. It is not known whether this drug passes into breast milk.

How Should Diflucan Be Taken?

Diflucan is available in several strengths and comes as a tablet (50, 100, 150 and 200 mg strength), liquid (350 or 1400 mg strength), or injection (2 mg per ml). Diflucan is taken once a day and may be taken for several weeks depending on the condition being treated.

How Should Nystatin Be Taken?

The adult and pediatric dose of Nystatin cream is to apply liberally to affected areas twice daily or as indicated until healing is complete. The adult and pediatric dose of Nystatin powder for candidal lesions is to apply two or three times daily until healing is complete. For fungal infection of the feet caused by Candida species, the powder should be dusted on the feet and in all foot wear.

SLIDESHOW

Fungal Skin Infections: Types, Symptoms, and Treatments See Slideshow
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References
Medical Editor: John P. Cunha, DO, FACOEP

SOURCE:

RxList. Diflucan Medication Guide.

https://www.rxlist.com/diflucan-drug.htm#medguide

RxList. Nystatin Product Monograph.

https://www.rxlist.com/nystatin-drug.htm

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