Last updated on RxList: 4/18/2017
Digibind Side Effects Center

Last reviewed on RxList 12/2/2015

Digibind (digoxin immune fab) contains antigen binding fragments and is used as an antidote to treat a life-threatening overdose of digoxin or digitoxin. Digibind is not for treating a mild digitalis overdose. Digibind may be available in generic form. Side effects of Digibind are uncommon. Tell your doctor if you experience serious side effects of Digibind including fever, high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling), low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness, or limp feeling), feeling short of breath even with mild exertion, swelling, or rapid weight gain.

The dosage of Digibind varies according to the amount of digoxin (or digitoxin) to be neutralized. The average dose used during clinical testing was 10 vials. It is only administered under a physician's supervision in emergency situations. Other drugs may interact with Digibind. Tell your doctor all prescription and over-the-counter medications and supplements you use. During pregnancy, Digibind should be taken only if prescribed. It may be harmful to a fetus. It is unknown if this drug passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.

Our Digibind (digoxin immune fab) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


In the U.S., 1 in every 4 deaths is caused by heart disease. See Answer
Digibind Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives, itching, skin redness; wheezing, cough, difficult breathing; fast heartbeats, feeling light-headed; swelling of your face, lips, tongue, or throat.

Tell your caregivers right away if you have:

  • fever, swollen glands, itching, joint pain, or not feeling well;
  • a light-headed feeling, like you might pass out;
  • heart problems--swelling, rapid weight gain, feeling short of breath; or
  • low potassium level--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling.

Common side effects may include:

  • heart problems; or
  • low potassium.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Digibind (Digoxin Immune Fab)


Heart Disease: Symptoms, Signs, and Causes See Slideshow
Digibind Professional Information


Allergic reactions to DIGIBIND (digoxin immune fab) have been reported rarely. Patients with a history of allergy, especially to antibiotics, appear to be at particular risk (see WARNINGS). In a few instances, low cardiac output states and congestive heart failure could have been exacerbated by withdrawal of the inotropic effects of digitalis. Hypokalemia may occur from re-activation of (sodium, potassium) ATPase (see Laboratory Tests). Patients with atrial fibrillation may develop a rapid ventricular response from withdrawal of the effects of digitalis on the atrioventricular node.4

Read the entire FDA prescribing information for Digibind (Digoxin Immune Fab)


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© Digibind Patient Information is supplied by Cerner Multum, Inc. and Digibind Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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