DigiFab Side Effects Center

Last updated on RxList: 5/19/2022
DigiFab Side Effects Center

What Is DigiFab?

DigiFab [Digoxin Immune Fab (Ovine)] is a digoxin immune fab (ovine) and is indicated for treatment of life-threatening or potentially life-threatening digoxin toxicity or overdose.

What Are Side Effects of DigiFab?

Dosage for DigiFab

Common side effects of DigiFab include:

What Drugs, Substances, or Supplements Interact with DigiFab?

Dose of DigiFab is determined by a physician and based on whether the amount of digoxin ingested is known, and whether the ingestion is chronic or acute.

DigiFab During Pregnancy or Breastfeeding

DigiFab may interact with other drugs. Tell your doctor all medications and supplements you use. During pregnancy, DigiFab should be administered only if prescribed. It is unknown if it would affect a fetus. It is unknown if DigiFab passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our DigiFab [Digoxin Immune Fab (Ovine)] Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

SLIDESHOW

Digestive Disorders: Common Misconceptions See Slideshow
DigiFab Professional Information

SIDE EFFECTS

The most common adverse reactions ( > 7%) related to DigiFab® administration are worsening congestive heart failure (13%), hypokalemia (13%) and worsening atrial fibrillation (7%).

Clinical Trial Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.

In the clinical trials of DigiFab®, 6 of 15 patients in the digoxin overdose study had a total of 17 adverse events. Three events occurred in one patient and consisted of the following: pulmonary edema, bilateral pleural effusion and renal failure. The events were determined to be likely due to the loss of digoxin inotropic support in combination with the patient's underlying medical condition. Of 8 healthy volunteers who received DigiFab®, two experienced an adverse reaction that was considered to be related to DigiFab®. The reactions were; one episode of phlebitis of the infusion-site vein and one episode of transient postural hypotension.

Read the entire FDA prescribing information for DigiFab (Ovine Lyophilized Powder for Intravenous Injection)

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© DigiFab Patient Information is supplied by Cerner Multum, Inc. and DigiFab Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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