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Diprolene AF

Last reviewed on RxList: 9/3/2020
Diprolene AF Side Effects Center

What Is Diprolene AF?

Diprolene AF (augmented betamethasone dipropionate) Cream 0.05% is a high-potency corticosteroid used to relieve inflammation and itchiness due to a skin disease caused by a reaction to other corticosteroids. Diprolene AF is available in generic form.

What Are Side Effects of Diprolene AF?

Common side effects of Diprolene AF include:

  • skin redness,
  • burning,
  • itching,
  • peeling,
  • irritation, and
  • dryness at the application area

Other side effects of Diprolene AF include thinning of your skin, blistering skin, or stretch marks.

Dosage for Diprolene AF

Recommended dosage of Diprolene AF is a thin layer applied to the affected area once or twice a day.

What Drugs, Substances, or Supplements Interact with Diprolene AF?

Prednisone and cyclosporine may interact with Diprolene AF. Tell your doctor all medications you take. Do not use Diprolene AF if you have an infection or sore on the affected area. Before using Diprolene AF tell your doctor if you have poor blood circulation, immune system problems, rosacea, or perioral dermatitis.

Diprolene AF During Pregnancy and Breastfeeding

If you are pregnant only use Diprolene AF if clearly needed. Talk to your doctor if you are breastfeeding before using Diprolene AF.

Additional Information

Our Diprolene AF (augmented betamethasone dipropionate) Cream 0.05% Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Diprolene AF Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using betamethasone and call your doctor at once if you have:

  • severe skin irritation where the medicine was applied; or
  • signs of skin infection (swelling, redness, warmth, oozing).

Your skin can absorb topical steroid medicine, which may cause steroid side effects throughout the body. Stop using betamethasone and call your doctor if you have:

  • blurred vision, tunnel vision, eye pain, or seeing halos around lights;
  • slow wound healing, thinning skin, increased body hair;
  • increased thirst or urination, dry mouth, fruity breath odor;
  • weight gain, puffiness in your face; or
  • muscle weakness, tired feeling, depression, anxiety, feeling irritable.

Steroids can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.

Common side effects may include:

  • itching, redness, burning, stinging, or blistering of treated skin;
  • skin bruising or shiny appearance; or
  • folliculitis (redness or crusting around your hair follicles).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Diprolene AF (Betamethasone)


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Diprolene AF Professional Information


Clinical Trials Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.

In controlled clinical trials, involving 242 adult subjects, the adverse reaction associated with the use of DIPROLENE AF Cream reported at a frequency of 0.4% was stinging. It occurred in 1 subject.

In a controlled clinical trial involving 67 pediatric subjects from 3 months to 12 years of age, the adverse reactions associated with the use of DIPROLENE AF Cream occurred in 7 of 67 (10%) subjects. Reported reactions included signs of skin atrophy (telangiectasia, bruising, shininess).

Postmarketing Experience

Because adverse reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Postmarketing reports for local adverse reactions to topical corticosteroids may also include: burning, itching, irritation, dryness, folliculitis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, secondary infection, hypertrichosis, skin atrophy, striae, and miliaria.

Hypersensitivity reactions, consisting of predominantly skin signs and symptoms, e.g., contact dermatitis, pruritus, bullous dermatitis, and erythematous rash have been reported.

Ophthalmic adverse reactions of cataracts, glaucoma, increased intraocular pressure, and central serous chorioretinopathy have been reported with the use of topical corticosteroids, including topical betamethasone products.

Read the entire FDA prescribing information for Diprolene AF (Betamethasone)

Related Resources for Diprolene AF

Related Health

Read the Diprolene AF User Reviews »

© Diprolene AF Patient Information is supplied by Cerner Multum, Inc. and Diprolene AF Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.


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