Diprolene Lotion Side Effects Center

Last updated on RxList: 4/28/2022
Diprolene Lotion Side Effects Center

What Is Diprolene Lotion?

Diprolene Lotion (betamethasone dipropionate) is a topical (for the skin) steroid used to treat inflammation caused by a number of conditions such as allergic reactions, eczema, and psoriasis. Diprolene Lotion is available in generic form.

What Are Side Effects of Diprolene Lotion?

Common side effects of Diprolene Lotion include:

  • burning,
  • itching,
  • irritation,
  • redness,
  • dryness, or
  • peeling at the application site when first applied to the skin

This should disappear in a few days as your body adjusts to Diprolene Lotion. Other side effects of Diprolene Lotion include thinning of your skin, blistering skin, or stretch marks.

Dosage for Diprolene Lotion

The recommended dose of Diprolene Lotion is to apply a few drops to the affected skin once or twice daily and massage lightly until the lotion disappears.

What Drugs, Substances, or Supplements Interact with Diprolene Lotion?

It is not likely other drugs you take orally or inject will have an effect on topically applied Diprolene Lotion. But many drugs can interact with each other. Tell your doctor all prescription and over-the-counter medications you use.

Diprolene Lotion During Pregnancy or Breastfeeding

During pregnancy, Diprolene should be used only when prescribed. It is unknown if this drug passes into breast milk when applied to the skin. Similar medications pass into breast milk when taken by mouth. Consult your doctor before breastfeeding.

Additional Information

Our Diprolene Lotion (betamethasone dipropionate) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Psoriasis causes the top layer of skin cells to become inflamed and grow too quickly and flake off. See Answer
Diprolene Lotion Consumer Information

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Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using betamethasone and call your doctor at once if you have:

  • severe skin irritation where the medicine was applied; or
  • signs of skin infection (swelling, redness, warmth, oozing).

Your skin can absorb topical steroid medicine, which may cause steroid side effects throughout the body. Stop using betamethasone and call your doctor if you have:

  • blurred vision, tunnel vision, eye pain, or seeing halos around lights;
  • slow wound healing, thinning skin, increased body hair;
  • increased thirst or urination, dry mouth, fruity breath odor;
  • weight gain, puffiness in your face; or
  • muscle weakness, tired feeling, depression, anxiety, feeling irritable.

Steroids can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.

Common side effects may include:

  • itching, redness, burning, stinging, or blistering of treated skin;
  • skin bruising or shiny appearance; or
  • folliculitis (redness or crusting around your hair follicles).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Diprolene Lotion Professional Information


Clinical Trials Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.

In controlled clinical trials, adverse reactions associated with the use of DIPROLENE Lotion reported at a frequency of less than 1% included erythema, folliculitis, pruritus, and vesiculation.

Postmarketing Experience

Because adverse reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Postmarketing reports for local adverse reactions to topical corticosteroids may also include: skin atrophy, striae, telangiectasias, burning, irritation, dryness, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, secondary infection, hypertrichosis, and miliaria.

Hypersensitivity reactions, consisting of predominantly skin signs and symptoms, e.g., contact dermatitis, pruritus, bullous dermatitis, and erythematous rash have been reported.

Ophthalmic adverse reactions of cataracts, glaucoma, increased intraocular pressure, and central serous chorioretinopathy have been reported with the use of topical corticosteroids, including topical betamethasone products.


No Information Provided

Read the entire FDA prescribing information for Diprolene Lotion (Betamethasone Dipropionate)

© Diprolene Lotion Patient Information is supplied by Cerner Multum, Inc. and Diprolene Lotion Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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