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Ditropan

Last reviewed on RxList: 1/24/2017
Ditropan Patient Information Including Side Effects

Brand Names: Ditropan, Ditropan XL, Urotrol

Generic Name: oxybutynin (oral) (Pronunciation: OX i BUE ti nin)

What is oxybutynin (Ditropan, Ditropan XL, Urotrol)?

Oxybutynin reduces muscle spasms of the bladder and urinary tract.

Oxybutynin is used to treat symptoms of overactive bladder, such as frequent or urgent urination, incontinence (urine leakage), and increased night-time urination.

Oxybutynin may also be used for purposes not listed in this medication guide.

What are the possible side effects of oxybutynin (Ditropan, Ditropan XL, Urotrol)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using oxybutynin and call your doctor at once if you have a serious side effect such as:

  • hot, dry skin and extreme thirst;
  • severe stomach pain or constipation;
  • blurred vision, eye pain, or seeing halos around lights;
  • pain or burning when you urinate; or
  • urinating less than usual or not at all.

Less serious side effects may include:

  • dry mouth;
  • dry eyes, blurred vision;
  • mild constipation;
  • diarrhea;
  • nausea, mild stomach pain or upset;
  • dizziness, drowsiness, weakness;
  • headache;
  • sleep problems; or
  • runny nose.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about oxybutynin (Ditropan, Ditropan XL, Urotrol)?

You should not use this medication if you are allergic to oxybutynin, or if you have untreated or uncontrolled narrow-angle glaucoma, a blockage in your digestive tract (stomach or intestines), or if you are unable to urinate.

Before using oxybutynin, tell your doctor if you have glaucoma, liver or kidney disease, an enlarged prostate, myasthenia gravis, ulcerative colitis, a blockage in your stomach or intestines, or a stomach disorder such as gastroesophageal reflux disease (GERD) or slow digestion.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Oxybutynin can decrease perspiration and you may be more prone to heat stroke.

This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

There are many other medicines that can interact with oxybutynin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

Stop using this medication and call your doctor if you have serious side effects such as hot and dry skin, extreme thirst, severe stomach pain or constipation, pain or burning when you urinate, or if you stop urinating.

Ditropan Patient Information including How Should I Take

What should I discuss with my healthcare provider before using oxybutynin (Ditropan, Ditropan XL, Urotrol)?

You should not use this medication if you are allergic to oxybutynin, or if you have:

  • untreated or uncontrolled narrow-angle glaucoma;
  • a blockage in your digestive tract (stomach or intestines); or
  • if you are unable to urinate.

To make sure you can safely take oxybutynin, tell your doctor if you have any of these other conditions:

  • glaucoma;
  • liver disease;
  • kidney disease;
  • an enlarged prostate;
  • ulcerative colitis;
  • a blockage in your stomach or intestines;
  • a muscle disorder such as myasthenia gravis; or
  • a stomach disorder such as gastroesophageal reflux disease (GERD) or slow digestion.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether oxybutynin passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take oxybutynin (Ditropan, Ditropan XL, Urotrol)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Take this medication with a full glass of water.

Oxybutynin may be taken with or without food.

Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking the pill may cause too much of the drug to be released at one time.

Measure liquid medicine with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Try to take this medication at the same time each day.

If you use the extended-release form of oxybutynin, you may notice what looks like part of a tablet in your stools. The tablet shell is not designed to be absorbed by the body, and may therefore pass into the stools without dissolving. This is a normal side effect of oxybutynin extended-release tablets.

Store at room temperature away from moisture and heat.

Ditropan Patient Information including If I Miss a Dose

What happens if I miss a dose (Ditropan, Ditropan XL, Urotrol)?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Ditropan, Ditropan XL, Urotrol)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include restlessness, tingly feeling, fever, uneven heart rate, vomiting, and urinating less than usual or not at all.

What should I avoid while using oxybutynin (Ditropan, Ditropan XL, Urotrol)?

Este medicamento puede causar visión borrosa y puede perjudicar su pensamiento o reacciones. Tenga cuidado al manejar o hacer otras actividades que demanden esté alerta y sea capaz de ver claramente.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Oxybutynin can decrease perspiration and you may be more prone to heat stroke.

What other drugs will affect oxybutynin (Ditropan, Ditropan XL, Urotrol)?

Before using oxybutynin, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by oxybutynin.

Tell your doctor about all other medicines you use, especially:

  • other bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), tolterodine (Detrol), or solifenacin (Vesicare);
  • glycopyrrolate (Robinul);
  • flecainide (Tambocor);
  • mepenzolate (Cantil);
  • thioridazine (Mellaril);
  • HIV /AIDS medicine such as nelfinavir (Viracept) or ritonavir (Norvir, Kaletra);
  • an antibiotic such as clarithromycin (Biaxin) or erythromycin (E.E.S., E-Mycin, Ery-Tab, Erythrocin);
  • an antifungal medication such as itraconazole (Sporanox) or ketoconazole (Nizoral);
  • atropine (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop);
  • bronchodilators such as ipratroprium (Atrovent) or tiotropium (Spiriva);
  • irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), or propantheline (Pro-Banthine); or
  • an antidepressant such as amitriptyline (Elavil, Etrafon), fluoxetine (Prozac), fluvoxamine (Luvox), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), paroxetine (Paxil), and others.

This list is not complete and there are many other drugs that can interact with oxybutynin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

Where can I get more information?

Your pharmacist can provide more information about oxybutynin.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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