Doryx vs. Minocin

Are Doryx and Minocin the Same Thing?

Doryx MPC (doxycycline hyclate delayed-release tablets) and Minocin (minocycline hydrochloride capsules) are tetracycline antibiotics indicated for severe acne, sexually transmitted infections, and other bacterial infections.

Doryx MPC is also used to treat rickettsial infections, respiratory tract infections, ophthalmic infections, anthrax [including inhalational anthrax (post-exposure)], alternative treatment for selected infections when penicillin is contraindicated, adjunctive therapy in acute intestinal amebiasis, and prophylaxis of malaria.

Minocin is also used to treat urinary tract infections (UTIs) and tick fever.

What Are Possible Side Effects of Doryx?

Common side effects of Doryx include:

What Are Possible Side Effects of Minocin?

Common side effects of Minocin include:

Tell your doctor if you have serious side effects of Minocin including:

  • stomach cramps,
  • diarrhea that is watery or bloody,
  • flu symptoms,
  • sores in your mouth and throat,
  • weakness,
  • dark colored urine,
  • unusual bleeding,
  • purple or red pinpoint spots under your skin,
  • fever,
  • skin rash,
  • bruising,
  • severe tingling or numbness,
  • muscle weakness,
  • loss of appetite,
  • yellowing of the skin or eyes,
  • chest pain,
  • irregular heart rhythm,
  • cough,
  • wheezing,
  • shortness of breath,
  • confusion,
  • vomiting,
  • swelling,
  • weight gain,
  • urinating less than usual or not at all,
  • headache or pain behind your eyes,
  • ringing in your ears,
  • vision problems,
  • joint pain or swelling with fever,
  • swollen glands,
  • muscle aches,
  • general ill feeling,
  • unusual thoughts or behavior,
  • seizures (convulsions), or
  • a severe skin reaction.

What is Doryx?

Doryx MPC (doxycycline hyclate delayed-release tablets) is a tetracycline class antibiotic indicated for rickettsial infections, sexually transmitted infections, respiratory tract infections, specific bacterial infections, ophthalmic infections anthrax [including inhalational anthrax (post-exposure)], alternative treatment for selected infections when penicillin is contraindicated, adjunctive therapy in acute intestinal amebiasis and severe acne, and prophylaxis of malaria.

What is Minocin?

Minocin (minocycline hydrochloride) is a tetracycline antibiotic used to treat many different bacterial infections, such as urinary tract infections, respiratory infections, skin infections, severe acne, gonorrhea, tick fever, chlamydia, and others.


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What Drugs Interact With Doryx?

Administration of botulinum toxin with other agents (for example, aminoglycosides, curare) that affect neuromuscular function may increase the effect of botulinum toxin.

What Drugs Interact With Minocin?

Minocin may interact with other antibiotics, acetaminophen (Tylenol), isotretinoin, methotrexate, antifungals, blood thinners, cholesterol medications, heart or blood pressure medicines, migraine headache medicines, or NSAIDs (nonsteroidal anti-inflammatory drugs). Tell your doctor all medications and supplements you use. Minocin should not be used during pregnancy. It could harm the fetus or cause permanent tooth discoloration later in life. Tell your doctor if you become pregnant during treatment. Minocin can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) while using minocycline.

How Should Doryx Be Taken?

The usual dosage of Doryx MPC is 240 mg on the first day of treatment (administered 120 mg every 12 hours) followed by a maintenance dose of 120 mg daily.

How Should Minocin Be Taken?

The usual dosage of Minocin is 200 mg initially followed by 100 mg every 12 hours.


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MaynePharma. Doryx Product Monograph.

FDA. Minocin Product Information.

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