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Dovonex Ointment

Last reviewed on RxList: 11/22/2016
Dovonex Ointment Side Effects Center

Last reviewed on RxList 02/16/2017

Dovonex (calcipotriene) is a synthetic topical (for the skin) form of vitamin D used to treat plaque psoriasis (psoriasis with scaly patches). Dovonex is available in generic form. Common side effects of Dovonex include:

  • burning,
  • itching,
  • rash,
  • irritation,
  • redness,
  • dry skin, or
  • peeling at the application site.

Tell your doctor if you have unlikely but serious side effects of Dovonex including:

  • skin thinning or discoloration,
  • stretch marks,
  • "hair bumps" (folliculitis),
  • unusual tiredness,
  • mental/mood changes, or
  • unexplained constipation.

Apply a thin layer of Dovonex ointment in a once or twice daily dose and rub in gently and completely. Avoid using harsh, abrasive, or irritating cleansers, perfumes, or cosmetics on the area you are treating. Other medicines, especially other topical medicines, may interact with Dovonex topical. Tell your doctor about any prescription or over-the-counter medicines or supplements you use. During pregnancy, Dovonex should be used only when prescribed. It is not known whether this drug passes into breast milk. Consult your doctor before breastfeeding.

Our Dovonex (calcipotriene) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Dovonex Ointment Consumer Information

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using calcipotriene topical and call your doctor at once if you have a serious side effect such as:

  • severe burning, stinging, or irritation after using this medication;
  • worsening of your skin condition; or
  • nausea, vomiting, stomach pain, loss of appetite, constipation, increased thirst or urination, muscle pain or weakness, joint pain, confusion, and feeling tired or restless.

Less serious side effects may include:

  • mild skin redness;
  • dry or peeling skin; or
  • mild rash or itching.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Dovonex Ointment (Calcipotriene Ointment)

Dovonex Ointment Professional Information


In controlled clinical trials, the most frequent adverse reactions reported for Dovonex® (calcipotriene ointment) were burning, itching and skin irritation, which occurred in approximately 10-15% of patients. Erythema, dry skin, peeling, rash, dermatitis, worsening of psoriasis including development of facial/scalp psoriasis were reported in 1 to 10% of patients. Other experiences reported in less than 1% of patients included skin atrophy, hyperpigmentation, hypercalcemia, and folliculitis. Once daily dosing has not been shown to be superior in safety to twice daily dosing.

Read the entire FDA prescribing information for Dovonex Ointment (Calcipotriene Ointment)

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© Dovonex Ointment Patient Information is supplied by Cerner Multum, Inc. and Dovonex Ointment Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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