Doxy 100 200

Last updated on RxList: 5/4/2020
Doxy 100 200 Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is Doxy 100 & 200?

Doxy 100 & 200 (doxycycline for injection) is a solution of a tetracycline antibiotic combined with ascorbic acid and mannitol used to treat or prevent infections from susceptible bacteria such as Rickettsiae, Mycoplasma pneumoniae, Haemophilus ducreyi, Yersinia pestis, Bartonella bacilliformis, Escherichia coli, Enterobacter aerogenes, Shigella species, Acinetobacter species, Haemophilus influenzae, Klebsiella species, anthrax due to Bacillus anthracis, Streptococcus species, Neisseria gonorrhoeae, N. meningitidis, Listeria monocytogenes, Clostridium species, and many others.

What Are Side Effects of Doxy 100 & 200?

Side effects of Doxy 100 & 200 include:

  • loss of appetite,
  • nausea,
  • vomiting,
  • diarrhea,
  • inflammation of the tongue,
  • problems swallowing,
  • rash, and
  • hypersensitivity reactions

Dosage for Doxy 100 & 200

The usual dosage of Doxy 100 & 200 for injection is 200 mg on the first day of treatment administered in one or two infusions. Subsequent daily dosage is 100 to 200 mg depending upon the severity of infection, with 200 mg administered in one or two infusions.

Doxy 100 & 200 In Children

The use of Doxy 100 & 200 for injection in children under 8 years is not recommended because safe conditions for its use have not been established.

What Drugs, Substances, or Supplements Interact with Doxy 100 & 200?

Doxy 100 & 200 may interact with other medicines.

Tell your doctor all medications and supplements you use.

Doxy 100 & 200 During Pregnancy and Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant before using Doxy 100 & 200; it may harm a fetus. Doxy 100 & 200 passes into breast milk, however, the extent of absorption by the nursing infant is unknown. Breastfeeding is not recommended while using Doxy 100 & 200.

Additional Information

Our Doxy 100 & 200 (doxycycline for injection) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Fungal Skin Infections: Types, Symptoms, and Treatments See Slideshow
Doxy 100 200 Consumer Information

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, flu-like symptoms, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. This reaction may occur several weeks after you began using doxycycline.

Call your doctor at once if you have:

  • severe stomach pain, diarrhea that is watery or bloody;
  • throat irritation, trouble swallowing;
  • chest pain, irregular heart rhythm, feeling short of breath;
  • little or no urination;
  • low white blood cell counts--fever, chills, swollen glands, body aches, weakness, pale skin, easy bruising or bleeding;
  • increased pressure inside the skull--severe headaches, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes; or
  • signs of liver or pancreas problems--loss of appetite, upper stomach pain (that may spread to your back), tiredness, nausea or vomiting, fast heart rate, dark urine, jaundice (yellowing of the skin or eyes).

Common side effects may include:

  • nausea, vomiting, upset stomach, loss of appetite;
  • mild diarrhea;
  • skin rash or itching;
  • darkened skin color; or
  • vaginal itching or discharge.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Doxy 100 200 (Doxycycline for Injection)


Bowel regularity means a bowel movement every day. See Answer
Doxy 100 200 Professional Information



Anorexia, nausea, vomiting, diarrhea, glossitis, dysphagia, enterocolitis and inflammatory lesions (with monilial overgrowth) in the anogenital region. Hepatotoxicity has been reported rarely. These reactions have been caused by both the oral and parenteral administration of tetracyclines.


Maculopapular and erythematous rashes. Exfoliative dermatitis has been reported but is uncommon. Photosensitivity is discussed above (see WARNINGS).

Renal Toxicity

Rise in BUN has been reported and is apparently dose related (see WARNINGS).

Hypersensitivity Reactions

Urticaria, angioneurotic edema, anaphylaxis, anaphylactoid purpura, pericarditis and exacerbation of systemic lupus erythematosus.

Bulging fontanels in infants and benign intracranial hypertension in adults have been reported in individuals receiving full therapeutic dosages. These conditions disappeared rapidly when the drug was discontinued.


Hemolytic anemia, thrombocytopenia, neutropenia and eosinophilia have been reported.

When given over prolonged periods, tetracyclines have been reported to produce brownblack microscopic discoloration of thyroid glands. No abnormalities of thyroid function studies are known to occur.

Read the entire FDA prescribing information for Doxy 100 200 (Doxycycline for Injection)

© Doxy 100 200 Patient Information is supplied by Cerner Multum, Inc. and Doxy 100 200 Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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