Drug interactions with atazanavir-cobicistat oral and eliglustat oral

atazanavir-cobicistat oral brand names and other generic formulations include:

Evotaz Oral

All generic drug interactions for atazanavir-cobicistat oral (lists will include brand and generic names):

eliglustat oral brand names and other generic formulations include:

Cerdelga Oral

All generic drug interactions for eliglustat oral (lists will include brand and generic names):
ContraindicatedNever use this combination of drugs because of high risk for dangerous interaction

atazanavir-cobicistat oral and eliglustat oral

atazanavir-cobicistat oral increases levels of eliglustat oral by altering drug metabolism. Your doctor will reduce the dose of eliglustat when it is given with drugs that can moderately reduce its breakdown. Do not combine with drugs that significantly reduce the breakdown of eliglustat.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
ContraindicatedContraindicated.

atazanavir-cobicistat oral and eliglustat oral

atazanavir-cobicistat oral increases levels of eliglustat oral by affecting hepatic enzyme CYP2D6 metabolism. Strong CYP3A4 inhibitors are contraindicated with eliglustat poor or intermediate metabolizers; reduce eliglustat dose from 84 mg BID to 84 mg once daily in extensive metabolizers; eliglustat is contraindicated if strong or moderate CYP2D6 inhibitors are given concomitantly with strong or moderate CYP3A inhibitors.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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