
atazanavir-cobicistat oral brand names and other generic formulations include:
Evotaz Oral
simvastatin oral brand names and other generic formulations include:
atazanavir-cobicistat oral and simvastatin oral
atazanavir-cobicistat oral will increase the level or effect of simvastatin oral by altering drug metabolism. Potential for serious reactions such as myopathy (muscular disease) including rhabdomyolysis (skeletal muscle damage).
atazanavir-cobicistat oral and simvastatin oral
atazanavir-cobicistat oral will increase the level or effect of simvastatin oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Potential for serious reactions such as myopathy including rhabdomyolysis
Check for more interactions with the Drug Interaction Checker
Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant